"Erythromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Descriptor ID |
D004917
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MeSH Number(s) |
D02.540.576.500.992
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Erythromycin".
Below are MeSH descriptors whose meaning is more specific than "Erythromycin".
This graph shows the total number of publications written about "Erythromycin" by people in this website by year, and whether "Erythromycin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2003 | 2 | 0 | 2 |
2004 | 1 | 0 | 1 |
2005 | 0 | 3 | 3 |
2006 | 1 | 0 | 1 |
2007 | 1 | 1 | 2 |
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Below are the most recent publications written about "Erythromycin" by people in Profiles.
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Sahm DF, Benninger MS, Evangelista AT, Yee YC, Thornsberry C, Brown NP. Antimicrobial resistance trends among sinus isolates of Streptococcus pneumoniae in the United States (2001-2005). Otolaryngol Head Neck Surg. 2007 Mar; 136(3):385-9.
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Gygax SE, Schuyler JA, Trama JP, Mordechai E, Adelson ME. Detection of erythromycin and clindamycin resistance genes in Group B Streptococcal clinical isolates and cervicovaginal-rectal swabs. Microb Drug Resist. 2007; 13(2):119-23.
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Gygax SE, Schuyler JA, Kimmel LE, Trama JP, Mordechai E, Adelson ME. Erythromycin and clindamycin resistance in group B streptococcal clinical isolates. Antimicrob Agents Chemother. 2006 May; 50(5):1875-7.
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Hammersmith KM, Cohen EJ, Blake TD, Laibson PR, Rapuano CJ. Blepharokeratoconjunctivitis in children. Arch Ophthalmol. 2005 Dec; 123(12):1667-70.
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Schott AF, Rae JM, Griffith KA, Hayes DF, Sterns V, Baker LH. Combination vinorelbine and capecitabine for metastatic breast cancer using a non-body surface area dosing scheme. Cancer Chemother Pharmacol. 2006 Jul; 58(1):129-35.
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Davies TA, Bush K, Sahm D, Evangelista A. Predominance of 23S rRNA mutants among non-erm, non-mef macrolide-resistant clinical isolates of Streptococcus pneumoniae collected in the United States in 1999-2000. Antimicrob Agents Chemother. 2005 Jul; 49(7):3031-3.
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Amato CS, Wang RY, Wright RO, Linakis JG. Evaluation of promotility agents to limit the gut bioavailability of extended-release acetaminophen. J Toxicol Clin Toxicol. 2004; 42(1):73-7.
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Veronese ML, Gillen LP, Dorval EP, Hauck WW, Waldman SA, Greenberg HE. Effect of mibefradil on CYP3A4 in vivo. J Clin Pharmacol. 2003 Oct; 43(10):1091-100.
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Veronese ML, Gillen LP, Burke JP, Dorval EP, Hauck WW, Pequignot E, Waldman SA, Greenberg HE. Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice. J Clin Pharmacol. 2003 Aug; 43(8):831-9.
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Lehman SS. Ophthalmia neonatorum associated with isoimmune neonatal neutropenia. J Pediatr Ophthalmol Strabismus. 2002 May-Jun; 39(3):181.