"Fetal Hemoglobin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypeptide subunits in comparison to normal adult hemoglobin, which has two alpha and two beta polypeptide subunits. Fetal hemoglobin concentrations can be elevated (usually above 0.5%) in children and adults affected by LEUKEMIA and several types of ANEMIA.
| Descriptor ID |
D005319
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| MeSH Number(s) |
D12.776.124.400.303 D12.776.422.316.762.320
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fetal Hemoglobin".
Below are MeSH descriptors whose meaning is more specific than "Fetal Hemoglobin".
This graph shows the total number of publications written about "Fetal Hemoglobin" by people in this website by year, and whether "Fetal Hemoglobin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fetal Hemoglobin" by people in Profiles.
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Peedin AR, Mazepa MA, Park YA, Weimer ET, Schmitz JL, Raval JS. Two cases of asymptomatic massive fetomaternal hemorrhage. Transfus Apher Sci. 2015 Apr; 52(2):208-10.
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Lanzkron S, Strouse JJ, Wilson R, Beach MC, Haywood C, Park H, Witkop C, Bass EB, Segal JB. Systematic review: Hydroxyurea for the treatment of adults with sickle cell disease. Ann Intern Med. 2008 Jun 17; 148(12):939-55.
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Adachi K, Zhao Y, Lakka V, Weiss MJ, Surrey S. Assembly of recently translated full-length and C-terminal truncated human gamma-globin chains with a pool of alpha-globin chains to form Hb F in a cell-free system. Arch Biochem Biophys. 2007 Jul 01; 463(1):60-7.
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Adachi K, Yang Y, Lakka V, Wehrli S, Reddy KS, Surrey S. Significance of beta116 His (G18) at alpha1beta1 contact sites for alphabeta assembly and autoxidation of hemoglobin. Biochemistry. 2003 Sep 02; 42(34):10252-9.
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Heeney MM, Delgrosso K, Robinson R, Johnson CA, Daeschner CW, Campbell TA, Surrey S, Ware RE. Interpretation of fetal hemoglobin only on newborn screening for hemoglobinopathy. J Pediatr Hematol Oncol. 2002 Aug-Sep; 24(6):499-502.
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Adachi K, Zhao Y, Surrey S. Assembly of human hemoglobin (Hb) beta- and gamma-globin chains expressed in a cell-free system with alpha-globin chains to form Hb A and Hb F. J Biol Chem. 2002 Apr 19; 277(16):13415-20.
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Setty BN, Stuart MJ. Eicosanoids in sickle cell disease: potential relevance of neutrophil leukotriene B4 to disease pathophysiology. J Lab Clin Med. 2002 Feb; 139(2):80-9.
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Adachi K, Zhao Y, Yamaguchi T, Surrey S. Assembly of gamma- with alpha-globin chains to form human fetal hemoglobin in vitro and in vivo. J Biol Chem. 2000 Apr 28; 275(17):12424-9.
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Adachi K, Konitzer P, Pang J, Reddy KS, Surrey S. Amino acids responsible for decreased 2,3-biphosphoglycerate binding to fetal hemoglobin. Blood. 1997 Oct 15; 90(8):2916-20.
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Adachi K, Pang J, Konitzer P, Surrey S. Polymerization of recombinant hemoglobin F gamma E6V and hemoglobin F gamma E6V, gamma Q87T alone, and in mixtures with hemoglobin S. Blood. 1996 Feb 15; 87(4):1617-24.