Free Radicals

"Free Radicals" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.

Descriptor ID	D005609
MeSH Number(s)	D01.339 D02.389
Concept/Terms	Free Radicals Free Radicals Radicals, Free

Below are MeSH descriptors whose meaning is more general than "Free Radicals".

Chemicals and Drugs [D]
Inorganic Chemicals [D01]
Free Radicals [D01.339]
Organic Chemicals [D02]
Free Radicals [D02.389]

Below are MeSH descriptors whose meaning is related to "Free Radicals".

Below are MeSH descriptors whose meaning is more specific than "Free Radicals".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Free Radicals" by people in this website by year, and whether "Free Radicals" was a major or minor topic of these publications.

Bar chart showing 13 publications over 9 distinct years, with a maximum of 3 publications in 2003

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2002	1	1
2003	3	3
2004	1	1
2005	1	1
2006	1	1
2007	1	1
2010	2	2
2013	2	2
2023	1	1

Below are the most recent publications written about "Free Radicals" by people in Profiles.

DiMartini ET, Kyker-Snowman K, Shreiber DI. A click chemistry-based, free radical-initiated delivery system for the capture and release of payloads. Drug Deliv. 2023 Dec; 30(1):2232952.

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Heckman KL, DeCoteau W, Estevez A, Reed KJ, Costanzo W, Sanford D, Leiter JC, Clauss J, Knapp K, Gomez C, Mullen P, Rathbun E, Prime K, Marini J, Patchefsky J, Patchefsky AS, Hailstone RK, Erlichman JS. Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain. ACS Nano. 2013 Dec 23; 7(12):10582-96.

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Thom SR, Bhopale VM, Milovanova TN, Yang M, Bogush M, Buerk DG. Nitric-oxide synthase-2 linkage to focal adhesion kinase in neutrophils influences enzyme activity and ?2 integrin function. J Biol Chem. 2013 Feb 15; 288(7):4810-8.

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Lehmann RK, Brounts LR, Lesperance KE, Eckert MJ, Lesperance RN, Beekley AC, Sebesta JA, Martin MJ. Hypoxemic versus normoxemic reperfusion in a large animal model of severe ischemia-reperfusion injury. J Surg Res. 2011 Apr; 166(2):194-8.

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Sataloff RT. Longevity: the disposable soma? Ear Nose Throat J. 2010 Jan; 89(1):8-10.

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Pressly ED, Rossin R, Hagooly A, Fukukawa K, Messmore BW, Welch MJ, Wooley KL, Lamm MS, Hule RA, Pochan DJ, Hawker CJ. Structural effects on the biodistribution and positron emission tomography (PET) imaging of well-defined (64)Cu-labeled nanoparticles comprised of amphiphilic block graft copolymers. Biomacromolecules. 2007 Oct; 8(10):3126-34.

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Kay CW, Elsässer C, Bittl R, Farrell SR, Thorpe C. Determination of the distance between the two neutral flavin radicals in augmenter of liver regeneration by pulsed ELDOR. J Am Chem Soc. 2006 Jan 11; 128(1):76-7.

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Larkin JD, Bock CW, Schaefer Iii HF. Assessing alkyl-, silyl-, and halo-substituent effects on the electron affinities of silyl radicals. J Phys Chem A. 2005 Nov 10; 109(44):10100-5.

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Sibille P, Tliba O, Boulard C. Early and transient cytotoxic response of peritoneal cells from Fasciola hepatica-infected rats. Vet Res. 2004 Sep-Oct; 35(5):573-84.

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Goldstein L, Teng ZP, Zeserson E, Patel M, Regan RF. Hemin induces an iron-dependent, oxidative injury to human neuron-like cells. J Neurosci Res. 2003 Jul 1; 73(1):113-21.

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