"Globosides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.
Descriptor ID |
D005915
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MeSH Number(s) |
D02.065.313.425 D09.400.410.420.525.200.425 D10.390.470.675.200.425 D10.570.877.360.612.200.425
|
Concept/Terms |
Cytolipins- Cytolipins
- Lacto-N-tetraosylceramide
- Lacto N tetraosylceramide
- Lactoneotetraosylceramide
- Lacto-N-neotetraosylceramide
- Lacto N neotetraosylceramide
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Below are MeSH descriptors whose meaning is more general than "Globosides".
Below are MeSH descriptors whose meaning is more specific than "Globosides".
This graph shows the total number of publications written about "Globosides" by people in this website by year, and whether "Globosides" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 1 | 2 |
1999 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Globosides" by people in Profiles.
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Ilyas AA, Gu Y, Dalakas MC, Quarles RH, Bhatt S. Induction of experimental ataxic sensory neuronopathy in cats by immunization with purified SGPG. J Neuroimmunol. 2008 Jan; 193(1-2):87-93.
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Weiss MD, Dalakas MC, Lauter CJ, Willison HJ, Quarles RH. Variability in the binding of anti-MAG and anti-SGPG antibodies to target antigens in demyelinating neuropathy and IgM paraproteinemia. J Neuroimmunol. 1999 Mar 1; 95(1-2):174-84.
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Dalakas MC, Quarles RH, Farrer RG, Dambrosia J, Soueidan S, Stein DP, Cupler E, Sekul EA, Otero C. A controlled study of intravenous immunoglobulin in demyelinating neuropathy with IgM gammopathy. Ann Neurol. 1996 Nov; 40(5):792-5.
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Farrer RG, Dalakas MC, Quarles RH. Multiple antibodies to nerve glycoconjugates in a patient with neuropathy and monoclonal IgA gammopathy. J Neuroimmunol. 1996 May; 66(1-2):71-6.
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Krupnick JG, Damjanov I, Damjanov A, Zhu ZM, Fenderson BA. Globo-series carbohydrate antigens are expressed in different forms on human and murine teratocarcinoma-derived cells. Int J Cancer. 1994 Dec 1; 59(5):692-8.
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Ilyas AA, Cook SD, Dalakas MC, Mithen FA. Anti-MAG IgM paraproteins from some patients with polyneuropathy associated with IgM paraproteinemia also react with sulfatide. J Neuroimmunol. 1992 Mar; 37(1-2):85-92.
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Zhu Z, Deng H, Fenderson BA, Nudelman ED, Tsui Z. Glycosphingolipids of human myometrium and endometrium and their changes during the menstrual cycle, pregnancy and ageing. J Reprod Fertil. 1990 Jan; 88(1):71-9.
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Fenderson BA, Andrews PW, Nudelman E, Clausen H, Hakomori S. Glycolipid core structure switching from globo- to lacto- and ganglio-series during retinoic acid-induced differentiation of TERA-2-derived human embryonal carcinoma cells. Dev Biol. 1987 Jul; 122(1):21-34.
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Ilyas AA, Dalakas MC, Brady RO, Quarles RH. Sulfated glucuronyl glycolipids reacting with anti-myelin-associated glycoprotein monoclonal antibodies including IgM paraproteins in neuropathy: species distribution and partial characterization of epitopes. Brain Res. 1986 Oct 15; 385(1):1-9.