"Guanidines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.
Descriptor ID |
D006146
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MeSH Number(s) |
D02.078.370
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Guanidines".
Below are MeSH descriptors whose meaning is more specific than "Guanidines".
This graph shows the total number of publications written about "Guanidines" by people in this website by year, and whether "Guanidines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Guanidines" by people in Profiles.
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Salvino JM, Srikanth YVV, Lou R, Oyer HM, Chen N, Kim FJ. Novel small molecule guanidine Sigma1 inhibitors for advanced prostate cancer. Bioorg Med Chem Lett. 2017 05 15; 27(10):2216-2220.
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Stewart SD, Lorenz GM, Catchot AL, Gore J, Cook D, Skinner J, Mueller TC, Johnson DR, Zawislak J, Barber J. Potential exposure of pollinators to neonicotinoid insecticides from the use of insecticide seed treatments in the mid-southern United States. Environ Sci Technol. 2014 Aug 19; 48(16):9762-9.
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Chae YC, Caino MC, Lisanti S, Ghosh JC, Dohi T, Danial NN, Villanueva J, Ferrero S, Vaira V, Santambrogio L, Bosari S, Languino LR, Herlyn M, Altieri DC. Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s. Cancer Cell. 2012 Sep 11; 22(3):331-44.
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Kang BH, Tavecchio M, Goel HL, Hsieh CC, Garlick DS, Raskett CM, Lian JB, Stein GS, Languino LR, Altieri DC. Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease. Br J Cancer. 2011 Feb 15; 104(4):629-34.
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Yuan Y, Jiao X, Lau WB, Wang Y, Christopher TA, Lopez BL, Ramachandrarao SP, Tao L, Ma XL. Thioredoxin glycation: A novel posttranslational modification that inhibits its antioxidant and organ protective actions. Free Radic Biol Med. 2010 Aug 1; 49(3):332-8.
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Burd R, Lavorgna SN, Daskalakis C, Wachsberger PR, Wahl ML, Biaglow JE, Stevens CW, Leeper DB. Tumor oxygenation and acidification are increased in melanoma xenografts after exposure to hyperglycemia and meta-iodo-benzylguanidine. Radiat Res. 2003 Mar; 159(3):328-35.
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Tian N, Gannon AW, Khalil RA, Manning RD. Mechanisms of salt-sensitive hypertension: role of renal medullary inducible nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol. 2003 Feb; 284(2):R372-9.
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Grover GJ, Parham CS, Whigan DB, Mitroka JG. BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs. J Pharmacol Exp Ther. 1996 Feb; 276(2):380-7.
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Funanage VL, Carango P, Shapiro IM, Tokuoka T, Tuan RS. Creatine kinase activity is required for mineral deposition and matrix synthesis in endochondral growth cartilage. Bone Miner. 1992 May; 17(2):228-36.