Heme Oxygenase (Decyclizing)
"Heme Oxygenase (Decyclizing)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt.
| Descriptor ID |
D006419
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| MeSH Number(s) |
D08.811.682.690.708.410
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Heme Oxygenase (Decyclizing)".
Below are MeSH descriptors whose meaning is more specific than "Heme Oxygenase (Decyclizing)".
This graph shows the total number of publications written about "Heme Oxygenase (Decyclizing)" by people in this website by year, and whether "Heme Oxygenase (Decyclizing)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 2 | 3 |
| 2004 | 4 | 1 | 5 |
| 2005 | 3 | 3 | 6 |
| 2006 | 3 | 1 | 4 |
| 2007 | 3 | 0 | 3 |
| 2008 | 0 | 3 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 4 | 0 | 4 |
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Below are the most recent publications written about "Heme Oxygenase (Decyclizing)" by people in Profiles.
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Cremers NA, Lundvig DM, van Dalen SC, Schelbergen RF, van Lent PL, Szarek WA, Regan RF, Carels CE, Wagener FA. Curcumin-induced heme oxygenase-1 expression prevents H2O2-induced cell death in wild type and heme oxygenase-2 knockout adipose-derived mesenchymal stem cells. Int J Mol Sci. 2014 Oct 08; 15(10):17974-99.
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Lundvig DM, Scharstuhl A, Cremers NA, Pennings SW, te Paske J, van Rheden R, van Run-van Breda C, Regan RF, Russel FG, Carels CE, Maltha JC, Wagener FA. Delayed cutaneous wound closure in HO-2 deficient mice despite normal HO-1 expression. J Cell Mol Med. 2014 Dec; 18(12):2488-98.
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Chen-Roetling J, Cai Y, Regan RF. Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage. BMC Res Notes. 2014 Aug 22; 7:561.
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Krishna CV, Singh J, Kumar S, Rattan S. Heme oxygenase-1 upregulation modulates tone and fibroelastic properties of internal anal sphincter. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 15; 307(6):G595-601.
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Chen-Roetling J, Cai Y, Lu X, Regan RF. Hemin uptake and release by neurons and glia. Free Radic Res. 2014 Feb; 48(2):200-5.
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Chen-Roetling J, Lu X, Regan KA, Regan RF. A rapid fluorescent method to quantify neuronal loss after experimental intracerebral hemorrhage. J Neurosci Methods. 2013 Jun 15; 216(2):128-36.
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Rodriguez F, Lopez B, Perez C, Fenoy FJ, Hernandez I, Stec DE, Li Volti G, Salom MG. Chronic tempol treatment attenuates the renal hemodynamic effects induced by a heme oxygenase inhibitor in streptozotocin diabetic rats. Am J Physiol Regul Integr Comp Physiol. 2011 Nov; 301(5):R1540-8.
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Lee JC, Kinniry PA, Arguiri E, Serota M, Kanterakis S, Chatterjee S, Solomides CC, Javvadi P, Koumenis C, Cengel KA, Christofidou-Solomidou M. Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice. Radiat Res. 2010 May; 173(5):590-601.
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Bellner L, Martinelli L, Halilovic A, Patil K, Puri N, Dunn MW, Regan RF, Schwartzman ML. Heme oxygenase-2 deletion causes endothelial cell activation marked by oxidative stress, inflammation, and angiogenesis. J Pharmacol Exp Ther. 2009 Dec; 331(3):925-32.
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Chen-Roetling J, Li Z, Chen M, Awe OO, Regan RF. Heme oxygenase activity and hemoglobin neurotoxicity are attenuated by inhibitors of the MEK/ERK pathway. Neuropharmacology. 2009 Apr; 56(5):922-8.