Below are the most recent publications written about "Hydroxylation" by people in Profiles.
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Carlier J, Diao X, Giorgetti R, Busard? FP, Huestis MA. Pyrrolidinyl Synthetic Cathinones a-PHP and 4F-a-PVP Metabolite Profiling Using Human Hepatocyte Incubations. Int J Mol Sci. 2020 Dec 28; 22(1).
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Presley BC, Logan BK, Jansen-Varnum SA. In Vitro Metabolic Profile Elucidation of Synthetic Cannabinoid APP-CHMINACA (PX-3). J Anal Toxicol. 2020 Apr 30; 44(3):226-236.
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Presley BC, Logan BK, Jansen-Varnum SA. In vitro Phase I metabolism of indazole carboxamide synthetic cannabinoid MDMB-CHMINACA via human liver microsome incubation and high-resolution mass spectrometry. Drug Test Anal. 2019 Aug; 11(8):1264-1276.
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Carlier J, Diao X, Huestis MA. Synthetic cannabinoid BB-22 (QUCHIC): Human hepatocytes metabolism with liquid chromatography-high resolution mass spectrometry detection. J Pharm Biomed Anal. 2018 Aug 05; 157:27-35.
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Diao X, Carlier J, Zhu M, Huestis MA. Human Hepatocyte Metabolism of Novel Synthetic Cannabinoids MN-18 and Its 5-Fluoro Analog 5F-MN-18. Clin Chem. 2017 Nov; 63(11):1753-1763.
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Gandhi AS, Wohlfarth A, Zhu M, Pang S, Castaneto M, Scheidweiler KB, Huestis MA. High-resolution mass spectrometric metabolite profiling of a novel synthetic designer drug, N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135), using cryopreserved human hepatocytes and assessment of metabolic stability with human liver microsomes. Drug Test Anal. 2015 Mar; 7(3):187-98.
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Desta Z, Moaddel R, Ogburn ET, Xu C, Ramamoorthy A, Venkata SL, Sanghvi M, Goldberg ME, Torjman MC, Wainer IW. Stereoselective and regiospecific hydroxylation of ketamine and norketamine. Xenobiotica. 2012 Nov; 42(11):1076-87.
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Wouters MA, Rigoutsos I, Chu CK, Feng LL, Sparrow DB, Dunwoodie SL. Evolution of distinct EGF domains with specific functions. Protein Sci. 2005 Apr; 14(4):1091-103.
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Chen Q, Tan E, Strauss JR, Zhang Z, Fenyk-Melody JE, Booth-Genthe C, Rushmore TH, Stearns RA, Evans DC, Baillie TA, Tang W. Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection. J Pharmacol Exp Ther. 2004 Oct; 311(1):307-14.
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Miller KK, Cai J, Ripp SL, Pierce WM, Rushmore TH, Prough RA. Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450. Drug Metab Dispos. 2004 Mar; 32(3):305-13.