"Citric Acid Cycle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of oxidative reactions in the breakdown of acetyl units derived from GLUCOSE; FATTY ACIDS; or AMINO ACIDS by means of tricarboxylic acid intermediates. The end products are CARBON DIOXIDE, water, and energy in the form of phosphate bonds.
| Descriptor ID |
D002952
|
| MeSH Number(s) |
G02.111.165 G03.295.342 G03.493.170
|
| Concept/Terms |
Citric Acid Cycle- Citric Acid Cycle
- Citric Acid Cycles
- Cycle, Citric Acid
- Cycles, Citric Acid
- Tricarboxylic Acid Cycle
- Cycle, Tricarboxylic Acid
- Cycles, Tricarboxylic Acid
- Tricarboxylic Acid Cycles
- Krebs Cycle
- Cycle, Krebs
|
Below are MeSH descriptors whose meaning is more general than "Citric Acid Cycle".
Below are MeSH descriptors whose meaning is more specific than "Citric Acid Cycle".
This graph shows the total number of publications written about "Citric Acid Cycle" by people in this website by year, and whether "Citric Acid Cycle" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Citric Acid Cycle" by people in Profiles.
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Ritterhoff J, McMillen T, Foundas H, Palkovacs R, Poschet G, Caudal A, Liu Y, Most P, Walker M, Tian R. 13C stable isotope tracing reveals distinct fatty acid oxidation pathways in proliferative versus oxidative cells. Am J Physiol Cell Physiol. 2025 01 01; 328(1):C168-C178.
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Hlavaty SI, Salcido KN, Pniewski KA, Mukha D, Ma W, Kannan T, Cassel J, Srikanth YVV, Liu Q, Kossenkov A, Salvino JM, Chen Q, Schug ZT. ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis. Cell Rep. 2024 12 24; 43(12):114988.
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Tavecchio M, Lisanti S, Bennett MJ, Languino LR, Altieri DC. Deletion of Cyclophilin D Impairs ?-Oxidation and Promotes Glucose Metabolism. Sci Rep. 2015 Oct 30; 5:15981.
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Agrawal B, Czymmek KJ, Sparks DL, Bais HP. Transient Influx of nickel in root mitochondria modulates organic acid and reactive oxygen species production in nickel hyperaccumulator Alyssum murale. J Biol Chem. 2013 Mar 08; 288(10):7351-62.
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Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics. Cell Cycle. 2011 Apr 15; 10(8):1271-86.
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McGrath JA. Biologic lessons from mutations in the Kreb's cycle enzyme, fumarate hydratase. J Invest Dermatol. 2003 Oct; 121(4):vii.