"Immunoglobulin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.
| Descriptor ID |
D007075
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| MeSH Number(s) |
D12.776.124.486.485.114.619.574 D12.776.124.790.651.114.619.574 D12.776.377.715.548.114.619.574
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin M".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin M".
This graph shows the total number of publications written about "Immunoglobulin M" by people in this website by year, and whether "Immunoglobulin M" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 2 | 0 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 2 | 3 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 4 | 0 | 4 |
| 2004 | 3 | 2 | 5 |
| 2006 | 1 | 1 | 2 |
| 2007 | 5 | 3 | 8 |
| 2008 | 0 | 3 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 3 | 4 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin M" by people in Profiles.
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Lemons AR, Siegel PD, Mhike M, Law BF, Hettick JM, Bledsoe TA, Nayak AP, Beezhold DH, Green BJ. A murine monoclonal antibody with broad specificity for occupationally relevant diisocyanates. J Occup Environ Hyg. 2014; 11(2):101-10.
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Johnson AC, Davison LM, Giltiay NV, Vareechon C, Li X, Jørgensen TN. Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease. Eur J Immunol. 2012 Jul; 42(7):1695-705.
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Maurer MA, Rakocevic G, Leung CS, Quast I, Lukacišin M, Goebels N, Münz C, Wardemann H, Dalakas M, Lünemann JD. Rituximab induces sustained reduction of pathogenic B cells in patients with peripheral nervous system autoimmunity. J Clin Invest. 2012 Apr 2; 122(4):1393-402.
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Colombo MJ, Abraham D, Shibuya A, Alugupalli KR. B1b lymphocyte-derived antibodies control Borrelia hermsii independent of Fca/µ receptor and in the absence of host cell contact. Immunol Res. 2011 Dec; 51(2-3):249-56.
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Nayak AP, Green BJ, Janotka E, Blachere FM, Vesper SJ, Beezhold DH, Schmechel D. Production and characterization of IgM monoclonal antibodies against hyphal antigens of Stachybotrys species. Hybridoma (Larchmt). 2011 Feb; 30(1):29-36.
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Moreira RK, Lee H, Stapp R, Ormsby A, Shah V. Immunohistochemical staining of inflammatory cells in liver biopsy specimens of patients with autoimmune hepatitis, primary biliary cirrhosis, and overlap syndromes. Am J Clin Pathol. 2010 Nov; 134(5):852-3.
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Colombo MJ, Sun G, Alugupalli KR. T-cell-independent immune responses do not require CXC ligand 13-mediated B1 cell migration. Infect Immun. 2010 Sep; 78(9):3950-6.
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Shriner AK, Liu H, Sun G, Guimond M, Alugupalli KR. IL-7-dependent B lymphocytes are essential for the anti-polysaccharide response and protective immunity to Streptococcus pneumoniae. J Immunol. 2010 Jul 1; 185(1):525-31.
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Lee H, Stapp RT, Ormsby AH, Shah VV. The usefulness of IgG and IgM immunostaining of periportal inflammatory cells (plasma cells and lymphocytes) for the distinction of autoimmune hepatitis and primary biliary cirrhosis and their staining pattern in autoimmune hepatitis-primary biliary cirrhosis overlap syndrome. Am J Clin Pathol. 2010 Mar; 133(3):430-7.
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Dalakas MC, Rakocevic G, Salajegheh M, Dambrosia JM, Hahn AF, Raju R, McElroy B. Placebo-controlled trial of rituximab in IgM anti-myelin-associated glycoprotein antibody demyelinating neuropathy. Ann Neurol. 2009 Mar; 65(3):286-93.