Immunoglobulins

"Immunoglobulins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.

Descriptor ID	D007136
MeSH Number(s)	D12.776.124.486.485 D12.776.124.790.651 D12.776.377.715.548
Concept/Terms	Immunoglobulins Immunoglobulins Immunoglobulin Globulins, Immune Immune Globulins

Below are MeSH descriptors whose meaning is more general than "Immunoglobulins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Immunoglobulins [D12.776.124.486.485]
Serum Globulins [D12.776.124.790]
Immunoglobulins [D12.776.124.790.651]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Immunoglobulins [D12.776.377.715.548]

Below are MeSH descriptors whose meaning is related to "Immunoglobulins".

Below are MeSH descriptors whose meaning is more specific than "Immunoglobulins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunoglobulins" by people in this website by year, and whether "Immunoglobulins" was a major or minor topic of these publications.

Bar chart showing 25 publications over 14 distinct years, with a maximum of 6 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	2	0	2
2002	1	0	1
2003	0	2	2
2004	1	0	1
2005	1	1	2
2006	1	0	1
2007	3	3	6
2008	3	0	3
2009	1	1	2
2010	1	0	1
2014	1	0	1
2017	0	1	1
2021	1	0	1
2023	0	1	1

Below are the most recent publications written about "Immunoglobulins" by people in Profiles.

Garvey EA, Arielle Best K, Naimi B, Duffy A, Hannikainen P, Kahn C, Farquhar D, Rosen M, Rabinowitz M, Fung S, Toskala E, Nyquist G. Benefits of Immunoglobulin (Ig) Replacement Therapy for Primary and Secondary Immunodeficiency in Chronic Rhinosinusitis. Otolaryngol Head Neck Surg. 2024 03; 170(3):968-971.

View in: PubMed
Campbell KS. Mystery Checkpoint Revealed: KIR3DL3 Finally Found a Ligand in HHLA2. Cancer Immunol Res. 2021 02; 9(2):128.

View in: PubMed
Kumar SK, Callander NS, Alsina M, Atanackovic D, Biermann JS, Chandler JC, Costello C, Faiman M, Fung HC, Gasparetto C, Godby K, Hofmeister C, Holmberg L, Holstein S, Huff CA, Kassim A, Liedtke M, Martin T, Omel J, Raje N, Reu FJ, Singhal S, Somlo G, Stockerl-Goldstein K, Treon SP, Weber D, Yahalom J, Shead DA, Kumar R. Multiple Myeloma, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2017 02; 15(2):230-269.

View in: PubMed
Pham-Thomas N, Pereira N, Powell AM, Croft DJ, Guilfoil DS, Montgomery OC. Outcomes of effective transmission of electronic prenatal records from the office to the hospital. Obstet Gynecol. 2014 Aug; 124(2 Pt 1):317-322.

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Hou Y, Rabquer BJ, Gerber ML, Del Galdo F, Jimenez SA, Haines GK, Barr WG, Massa MC, Seibold JR, Koch AE. Junctional adhesion molecule-A is abnormally expressed in diffuse cutaneous systemic sclerosis skin and mediates myeloid cell adhesion. Ann Rheum Dis. 2010 Jan; 69(1):249-54.

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Singh J, Mehendiratta V, Del Galdo F, Jimenez SA, Cohen S, DiMarino AJ, Rattan S. Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1206-13.

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Kino T, Takatori H, Manoli I, Wang Y, Tiulpakov A, Blackman MR, Su YA, Chrousos GP, DeCherney AH, Segars JH. Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5. Sci Signal. 2009 Feb 10; 2(57):ra5.

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Naik UP, Naik MU. Putting the brakes on cancer cell migration: JAM-A restrains integrin activation. Cell Adh Migr. 2008 Oct-Dec; 2(4):249-51.

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Naik MU, Naik TU, Suckow AT, Duncan MK, Naik UP. Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion. Cancer Res. 2008 Apr 01; 68(7):2194-203.

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Naik TU, Naik MU, Naik UP. Junctional adhesion molecules in angiogenesis. Front Biosci. 2008 Jan 01; 13:258-62.

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