Below are the most recent publications written about "Isomerases" by people in Profiles.
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Baas BJ, Medellin BP, LeVieux JA, Erwin K, Lancaster EB, Johnson WH, Kaoud TS, Moreno RY, de Ruijter M, Babbitt PC, Zhang YJ, Whitman CP. Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications. Biochemistry. 2021 06 08; 60(22):1776-1786.
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Stack TMM, Li W, Johnson WH, Zhang YJ, Whitman CP. Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry. 2018 Feb 13; 57(6):1012-1021.
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Burks EA, Yan W, Johnson WH, Li W, Schroeder GK, Min C, Gerratana B, Zhang Y, Whitman CP. Kinetic, crystallographic, and mechanistic characterization of TomN: elucidation of a function for a 4-oxalocrotonate tautomerase homologue in the tomaymycin biosynthetic pathway. Biochemistry. 2011 Sep 06; 50(35):7600-11.
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Wang SC, Johnson WH, Czerwinski RM, Stamps SL, Whitman CP. Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions. Biochemistry. 2007 Oct 23; 46(42):11919-29.
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Poelarends GJ, Almrud JJ, Serrano H, Darty JE, Johnson WH, Hackert ML, Whitman CP. Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase. Biochemistry. 2006 Jun 27; 45(25):7700-8.
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Almrud JJ, Poelarends GJ, Johnson WH, Serrano H, Hackert ML, Whitman CP. Crystal structures of the wild-type, P1A mutant, and inactivated malonate semialdehyde decarboxylase: a structural basis for the decarboxylase and hydratase activities. Biochemistry. 2005 Nov 15; 44(45):14818-27.
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Johnson WH, Wang SC, Stanley TM, Czerwinski RM, Almrud JJ, Poelarends GJ, Murzin AG, Whitman CP. 4-Oxalocrotonate tautomerase, its homologue YwhB, and active vinylpyruvate hydratase: synthesis and evaluation of 2-fluoro substrate analogues. Biochemistry. 2004 Aug 17; 43(32):10490-501.
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Poelarends GJ, Serrano H, Person MD, Johnson WH, Murzin AG, Whitman CP. Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases. Biochemistry. 2004 Jan 27; 43(3):759-72.
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Wang SC, Johnson WH, Czerwinski RM, Whitman CP. Reactions of 4-oxalocrotonate tautomerase and YwhB with 3-halopropiolates: analysis and implications. Biochemistry. 2004 Jan 27; 43(3):748-58.
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Wang SC, Johnson WH, Whitman CP. The 4-oxalocrotonate tautomerase- and YwhB-catalyzed hydration of 3E-haloacrylates: implications for the evolution of new enzymatic activities. J Am Chem Soc. 2003 Nov 26; 125(47):14282-3.