Phosphatidylcholine-Sterol O-Acyltransferase
"Phosphatidylcholine-Sterol O-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma.
Descriptor ID |
D007862
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MeSH Number(s) |
D08.811.913.050.625
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Concept/Terms |
Phosphatidylcholine-Sterol O-Acyltransferase- Phosphatidylcholine-Sterol O-Acyltransferase
- O-Acyltransferase, Phosphatidylcholine-Sterol
- Phosphatidylcholine Sterol O Acyltransferase
- Lecithin Cholesterol Acyltransferase
- Acyltransferase, Lecithin Cholesterol
- Cholesterol Acyltransferase, Lecithin
- Lecithin Acyltransferase
- Acyltransferase, Lecithin
- Cholesterol Ester Lysolecithin Acyltransferase
- Phosophatidylcholine-Sterol Acyltransferase
- Acyltransferase, Phosophatidylcholine-Sterol
- Phosophatidylcholine Sterol Acyltransferase
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylcholine-Sterol O-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylcholine-Sterol O-Acyltransferase".
This graph shows the total number of publications written about "Phosphatidylcholine-Sterol O-Acyltransferase" by people in this website by year, and whether "Phosphatidylcholine-Sterol O-Acyltransferase" was a major or minor topic of these publications.
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click here.
Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphatidylcholine-Sterol O-Acyltransferase" by people in Profiles.
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Trieb M, Kornej J, Knuplez E, Hindricks G, Thiele H, Sommer P, Scharnagl H, Dagres N, Dinov B, Bollmann A, Husser D, Marsche G, Buettner P. Atrial fibrillation is associated with alterations in HDL function, metabolism, and particle number. Basic Res Cardiol. 2019 05 08; 114(4):27.
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Vargas-Alarcon G, Perez-Mendez O, Herrera-Maya G, Garcia-Sanchez C, Martinez-Rios MA, Peña-Duque MA, Posadas-Sanchez R, Posadas-Romero C, Escobedo G, Fragoso JM. CETP and LCAT Gene Polymorphisms Are Associated with High-Density Lipoprotein Subclasses and Acute Coronary Syndrome. Lipids. 2018 02; 53(2):157-166.
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Ricciardi R, Veal TM, Anwaruddin S, Wheeler SM, Foley DP, Donohue SE, Quarfordt SH, Meyers WC. Porcine hepatic phospholipid efflux during reperfusion after cold ischemia. J Surg Res. 2002 Mar; 103(1):79-88.
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Frank PG, Marcel YL. Apolipoprotein A-I: structure-function relationships. J Lipid Res. 2000 Jun; 41(6):853-72.
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Frank PG, N'Guyen D, Franklin V, Neville T, Desforges M, Rassart E, Sparks DL, Marcel YL. Importance of central alpha-helices of human apolipoprotein A-I in the maturation of high-density lipoproteins. Biochemistry. 1998 Sep 29; 37(39):13902-9.