Ligands

"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)

Descriptor ID	D008024
MeSH Number(s)	D27.720.470.480
Concept/Terms	Ligands Ligands

Below are MeSH descriptors whose meaning is more general than "Ligands".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Specialty Uses of Chemicals [D27.720]
Laboratory Chemicals [D27.720.470]
Ligands [D27.720.470.480]

Below are MeSH descriptors whose meaning is related to "Ligands".

Below are MeSH descriptors whose meaning is more specific than "Ligands".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.

Bar chart showing 141 publications over 23 distinct years, with a maximum of 15 publications in 2003 and 2004 and 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1998	0	3	3
1999	0	2	2
2000	0	2	2
2001	0	6	6
2002	1	7	8
2003	1	14	15
2004	0	15	15
2005	0	15	15
2006	1	6	7
2007	0	7	7
2008	0	7	7
2009	1	11	12
2010	0	9	9
2011	0	7	7
2012	0	4	4
2013	0	5	5
2014	0	2	2
2015	0	3	3
2016	0	1	1
2017	0	4	4
2020	0	1	1
2021	0	5	5

Below are the most recent publications written about "Ligands" by people in Profiles.

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Kuhn M, MacEwan D, Monie TP, Papapetropoulos A, Potter LR, Schmidt HHHW, Szabo C, Waldman SA. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors. Br J Pharmacol. 2021 Oct; 178 Suppl 1:S264-S312.

View in: PubMed
Staquicini FI, Hajitou A, Driessen WH, Proneth B, Cardó-Vila M, Staquicini DI, Markosian C, Hoh M, Cortez M, Hooda-Nehra A, Jaloudi M, Silva IT, Buttura J, Nunes DN, Dias-Neto E, Eckhardt B, Ruiz-Ramírez J, Dogra P, Wang Z, Cristini V, Trepel M, Anderson R, Sidman RL, Gelovani JG, Cristofanilli M, Hortobagyi GN, Bhujwalla ZM, Burley SK, Arap W, Pasqualini R. Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer. Elife. 2021 06 01; 10.

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Pak ES, Jeong LS, Hou X, Tripathi SK, Lee J, Ha H. Dual Actions of A2A and A3 Adenosine Receptor Ligand Prevents Obstruction-Induced Kidney Fibrosis in Mice. Int J Mol Sci. 2021 May 26; 22(11).

View in: PubMed
Ramos-Ramírez P, Malmhäll C, Tliba O, Rådinger M, Bossios A. Adiponectin/AdipoR1 Axis Promotes IL-10 Release by Human Regulatory T Cells. Front Immunol. 2021; 12:677550.

View in: PubMed
Sharma P, Penn RB. Can GPCRs Be Targeted to Control Inflammation in Asthma? Adv Exp Med Biol. 2021; 1304:1-20.

View in: PubMed
Kushwaha P, Kim S, Foxa GE, Michalski MN, Williams BO, Tomlinson RE, Riddle RC. Frizzled-4 is required for normal bone acquisition despite compensation by Frizzled-8. J Cell Physiol. 2020 10; 235(10):6673-6683.

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Liu T, Angelo JM, Lin DQ, Lenhoff AM, Yao SJ. Characterization of dextran-grafted hydrophobic charge-induction resins: Structural properties, protein adsorption and transport. J Chromatogr A. 2017 Sep 29; 1517:44-53.

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Aka AA, Rappaport JA, Pattison AM, Sato T, Snook AE, Waldman SA. Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer. Expert Rev Clin Pharmacol. 2017 May; 10(5):549-557.

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Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG. Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation. ACS Chem Biol. 2017 05 19; 12(5):1353-1362.

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Kim FJ, Maher CM. Sigma1 Pharmacology in the Context of Cancer. Handb Exp Pharmacol. 2017; 244:237-308.

View in: PubMed

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