"Lipoproteins, HDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.
| Descriptor ID |
D008075
|
| MeSH Number(s) |
D10.532.432 D12.776.521.479
|
| Concept/Terms |
Lipoproteins, HDL- Lipoproteins, HDL
- HDL Lipoproteins
- Heavy Lipoproteins
- Lipoproteins, Heavy
- High-Density Lipoproteins
- High Density Lipoproteins
- Lipoproteins, High-Density
- alpha-Lipoproteins
- alpha Lipoproteins
|
Below are MeSH descriptors whose meaning is more general than "Lipoproteins, HDL".
Below are MeSH descriptors whose meaning is more specific than "Lipoproteins, HDL".
This graph shows the total number of publications written about "Lipoproteins, HDL" by people in this website by year, and whether "Lipoproteins, HDL" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2001 | 2 | 0 | 2 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipoproteins, HDL" by people in Profiles.
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Duffy D, Holmes DN, Roe MT, Peterson ED. The impact of high-density lipoprotein cholesterol levels on long-term outcomes after non-ST-elevation myocardial infarction. Am Heart J. 2012 Apr; 163(4):705-13.
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Chervoneva I, Vishnyakov M. Constrained S-estimators for linear mixed effects models with covariance components. Stat Med. 2011 Jun 30; 30(14):1735-50.
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Baker AD, Malur A, Barna BP, Ghosh S, Kavuru MS, Malur AG, Thomassen MJ. Targeted PPAR{gamma} deficiency in alveolar macrophages disrupts surfactant catabolism. J Lipid Res. 2010 Jun; 51(6):1325-31.
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Frank PG, Pavlides S, Cheung MW, Daumer K, Lisanti MP. Role of caveolin-1 in the regulation of lipoprotein metabolism. Am J Physiol Cell Physiol. 2008 Jul; 295(1):C242-8.
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Duffy D, Rader DJ. Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport. Circulation. 2006 Feb 28; 113(8):1140-50.
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Duffy D, Rader DJ. Drugs in development: targeting high-density lipoprotein metabolism and reverse cholesterol transport. Curr Opin Cardiol. 2005 Jul; 20(4):301-6.
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Thompson PD, Buchner D, Pina IL, Balady GJ, Williams MA, Marcus BH, Berra K, Blair SN, Costa F, Franklin B, Fletcher GF, Gordon NF, Pate RR, Rodriguez BL, Yancey AK, Wenger NK. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: a statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity). Circulation. 2003 Jun 24; 107(24):3109-16.
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Frank PG, Pedraza A, Cohen DE, Lisanti MP. Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels. Biochemistry. 2001 Sep 11; 40(36):10892-900.
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Frank PG, Galbiati F, Volonte D, Razani B, Cohen DE, Marcel YL, Lisanti MP. Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins. Am J Physiol Cell Physiol. 2001 May; 280(5):C1204-14.
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Frank PG, N'Guyen D, Franklin V, Neville T, Desforges M, Rassart E, Sparks DL, Marcel YL. Importance of central alpha-helices of human apolipoprotein A-I in the maturation of high-density lipoproteins. Biochemistry. 1998 Sep 29; 37(39):13902-9.