"Lymphotoxin-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.
| Descriptor ID |
D008233
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| MeSH Number(s) |
D12.644.276.374.480.438 D12.644.276.374.750.500 D12.776.467.374.480.438 D12.776.467.374.750.500 D23.529.374.480.438 D23.529.374.750.500
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| Concept/Terms |
Lymphotoxin-alpha- Lymphotoxin-alpha
- Lymphotoxin alpha
- Lymphotoxin
- Tumor Necrosis Factor-beta
- Tumor Necrosis Factor beta
- TNF-beta
- Tumor Necrosis Factor Ligand Superfamily Member 1
- alpha-Lymphotoxin
- alpha Lymphotoxin
- TNF Superfamily, Member 1
Lymphotoxin-alpha3- Lymphotoxin-alpha3
- Lymphotoxin alpha3
- Soluble Lymphotoxin-alpha
- Lymphotoxin-alpha, Soluble
- Soluble Lymphotoxin alpha
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Below are MeSH descriptors whose meaning is more general than "Lymphotoxin-alpha".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin-alpha".
This graph shows the total number of publications written about "Lymphotoxin-alpha" by people in this website by year, and whether "Lymphotoxin-alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
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Below are the most recent publications written about "Lymphotoxin-alpha" by people in Profiles.
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Zhang Y, Zhao J, Lau WB, Jiao LY, Liu B, Yuan Y, Wang X, Gao E, Koch WJ, Ma XL, Wang Y. Tumor necrosis factor-a and lymphotoxin-a mediate myocardial ischemic injury via TNF receptor 1, but are cardioprotective when activating TNF receptor 2. PLoS One. 2013; 8(5):e60227.
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Lau WB, Zhang Y, Zhao J, Liu B, Wang X, Yuan Y, Christopher TA, Lopez B, Gao E, Koch WJ, Ma XL, Wang Y. Lymphotoxin-a is a novel adiponectin expression suppressor following myocardial ischemia/reperfusion. Am J Physiol Endocrinol Metab. 2013 Mar 15; 304(6):E661-7.
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Rosenbloom J, Castro SV, Jimenez SA. Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies. Ann Intern Med. 2010 Feb 02; 152(3):159-66.
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Lee KM, Park SK, Hamajima N, Tajima K, Yoo KY, Shin A, Noh DY, Ahn SH, Hirvonen A, Kang D. Genetic polymorphisms of TGF-beta1 & TNF-beta and breast cancer risk. Breast Cancer Res Treat. 2005 Mar; 90(2):149-55.
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Demoor-Fossard M, Gal?ra P, Santra M, Iozzo RV, Pujol JP, R?dini F. A composite element binding the vitamin D receptor and the retinoic X receptor alpha mediates the transforming growth factor-beta inhibition of decorin gene expression in articular chondrocytes. J Biol Chem. 2001 Oct 05; 276(40):36983-92.
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Vindevoghel L, Lechleider RJ, Kon A, de Caestecker MP, Uitto J, Roberts AB, Mauviel A. SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14769-74.
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Mauviel A, Reitamo S, Remitz A, Lapi?re JC, Ceska M, Baggiolini M, Walz A, Evans CH, Uitto J. Leukoregulin, a T cell-derived cytokine, induces IL-8 gene expression and secretion in human skin fibroblasts. Demonstration and secretion in human skin fibroblasts. Demonstration of enhanced NF-kappa B binding and NF-kappa B-driven promoter activity. J Immunol. 1992 Nov 01; 149(9):2969-76.