Nucleic Acid Hybridization

"Nucleic Acid Hybridization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)

Descriptor ID	D009693
MeSH Number(s)	E05.393.661 G02.111.611
Concept/Terms	Nucleic Acid Hybridization Nucleic Acid Hybridization Acid Hybridization, Nucleic Acid Hybridizations, Nucleic Hybridization, Nucleic Acid Hybridizations, Nucleic Acid Nucleic Acid Hybridizations Genomic Hybridization Genomic Hybridization Genomic Hybridizations Hybridization, Genomic Hybridizations, Genomic

Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Hybridization".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Nucleic Acid Hybridization [E05.393.661]
Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Nucleic Acid Hybridization [G02.111.611]

Below are MeSH descriptors whose meaning is related to "Nucleic Acid Hybridization".

Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Hybridization".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nucleic Acid Hybridization" by people in this website by year, and whether "Nucleic Acid Hybridization" was a major or minor topic of these publications.

Bar chart showing 68 publications over 19 distinct years, with a maximum of 7 publications in 2003 and 2005 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	2	2	4
1997	0	5	5
1998	1	4	5
1999	1	2	3
2000	0	4	4
2001	0	1	1
2002	3	0	3
2003	0	7	7
2004	0	3	3
2005	2	5	7
2006	2	4	6
2007	0	7	7
2008	0	4	4
2012	0	2	2
2014	0	1	1
2016	1	0	1
2017	0	1	1
2018	0	2	2

Below are the most recent publications written about "Nucleic Acid Hybridization" by people in Profiles.

Gao Z, Xia H, Zauberman J, Tomaiuolo M, Ping J, Zhang Q, Ducos P, Ye H, Wang S, Yang X, Lubna F, Luo Z, Ren L, Johnson ATC. Detection of Sub-fM DNA with Target Recycling and Self-Assembly Amplification on Graphene Field-Effect Biosensors. Nano Lett. 2018 06 13; 18(6):3509-3515.

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Ozdemir AY, Rusanov T, Kent T, Siddique LA, Pomerantz RT. Polymerase ?-helicase efficiently unwinds DNA and RNA-DNA hybrids. J Biol Chem. 2018 04 06; 293(14):5259-5269.

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Orenstein A, Berlyoung AS, Rastede EE, Pham HH, Fouquerel E, Murphy CT, Leibowitz BJ, Yu J, Srivastava T, Armitage BA, Opresko PL. ?PNA FRET Pair Miniprobes for Quantitative Fluorescent In Situ Hybridization to Telomeric DNA in Cells and Tissue. Molecules. 2017 Dec 02; 22(12).

View in: PubMed
Petruk S, Fenstermaker TK, Black KL, Brock HW, Mazo A. Detection of RNA-DNA association by a proximity ligation-based method. Sci Rep. 2016 06 03; 6:27313.

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Sonar MV, Wampole ME, Jin YY, Chen CP, Thakur ML, Wickstrom E. Fluorescence detection of KRAS2 mRNA hybridization in lung cancer cells with PNA-peptides containing an internal thiazole orange. Bioconjug Chem. 2014 Sep 17; 25(9):1697-708.

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Schneider JS, Anderson DW, Talsania K, Mettil W, Vadigepalli R. Effects of developmental lead exposure on the hippocampal transcriptome: influences of sex, developmental period, and lead exposure level. Toxicol Sci. 2012 Sep; 129(1):108-25.

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Navenot JM, Evans B, Oishi S, Setsuda S, Fujii N, Peiper SC. The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma. Melanoma Res. 2012 Apr; 22(2):140-50.

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Lahoud G, Arar K, Hou YM, Gamper H. RecA-mediated strand invasion of DNA by oligonucleotides substituted with 2-aminoadenine and 2-thiothymine. Nucleic Acids Res. 2008 Dec; 36(21):6806-15.

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Dagvadorj A, Tan SH, Liao Z, Cavalli LR, Haddad BR, Nevalainen MT. Androgen-regulated and highly tumorigenic human prostate cancer cell line established from a transplantable primary CWR22 tumor. Clin Cancer Res. 2008 Oct 01; 14(19):6062-72.

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Battistella S, Damin F, Chiari M, Delgrosso K, Surrey S, Fortina P, Ferrari M, Cremonesi L. Genotyping beta-globin gene mutations on copolymer-coated glass slides with the ligation detection reaction. Clin Chem. 2008 Oct; 54(10):1657-63.

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