Platelet Aggregation

"Platelet Aggregation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.

Descriptor ID	D010974
MeSH Number(s)	G09.188.370.687 G09.188.390.600.640
Concept/Terms	Platelet Aggregation Platelet Aggregation Aggregation, Platelet

Below are MeSH descriptors whose meaning is more general than "Platelet Aggregation".

Biological Sciences [G]
Circulatory and Respiratory Physiological Phenomena [G09]
Blood Physiological Phenomena [G09.188]
Hemorheology [G09.188.370]
Platelet Aggregation [G09.188.370.687]
Hemostasis [G09.188.390]
Platelet Activation [G09.188.390.600]
Platelet Aggregation [G09.188.390.600.640]

Below are MeSH descriptors whose meaning is related to "Platelet Aggregation".

Below are MeSH descriptors whose meaning is more specific than "Platelet Aggregation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Platelet Aggregation" by people in this website by year, and whether "Platelet Aggregation" was a major or minor topic of these publications.

Bar chart showing 48 publications over 24 distinct years, with a maximum of 4 publications in 2000 and 2018 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	0	2	2
1999	0	3	3
2000	0	4	4
2001	0	1	1
2002	0	1	1
2003	1	2	3
2004	0	2	2
2006	1	1	2
2008	0	2	2
2010	0	1	1
2011	0	1	1
2012	1	1	2
2013	0	1	1
2014	2	1	3
2015	0	2	2
2016	2	1	3
2017	0	1	1
2018	2	2	4
2019	1	3	4
2020	0	1	1
2021	1	0	1
2022	1	1	2
2024	1	0	1

Below are the most recent publications written about "Platelet Aggregation" by people in Profiles.

Wurtzel JGT, Lazar S, Askari S, Zhao X, Severa J, Ayombil F, Michael JV, Camire RM, McKenzie SE, Stalker TJ, Ma P, Goldfinger LE. Plasma growth factors maintain constitutive translation in platelets to regulate reactivity and thrombotic potential. Blood Adv. 2024 03 26; 8(6):1550-1566.

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Zhao X, Cooper M, Michael JV, Yarman Y, Baltz A, Chuprun JK, Koch WJ, McKenzie SE, Tomaiuolo M, Stalker TJ, Zhu L, Ma P. GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y12. Blood Adv. 2022 08 09; 6(15):4524-4536.

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Renna SA, Michael JV, Kong X, Ma L, Ma P, Nieman MT, Edelstein LC, McKenzie SE. Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice. J Thromb Haemost. 2022 05; 20(5):1236-1247.

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Abraham S, Ma L, Kong X, Askari S, Edelstein LC, McKenzie SE. PCTP contributes to human platelet activation by enhancing dense granule secretion. Thromb Res. 2021 06; 202:67-73.

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Patel P, Shaik NF, Zhou Y, Golla K, McKenzie SE, Naik UP. Apoptosis signal-regulating kinase 1 regulates immune-mediated thrombocytopenia, thrombosis, and systemic shock. J Thromb Haemost. 2020 11; 18(11):3013-3028.

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Boone BA, Murthy P, Miller-Ocuin JL, Liang X, Russell KL, Loughran P, Gawaz M, Lotze MT, Zeh HJ, Vogel S. The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth. Ann Hematol. 2019 Jul; 98(7):1603-1610.

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Basak I, Bhatlekar S, Manne BK, Stoller M, Hugo S, Kong X, Ma L, Rondina MT, Weyrich AS, Edelstein LC, Bray PF. miR-15a-5p regulates expression of multiple proteins in the megakaryocyte GPVI signaling pathway. J Thromb Haemost. 2019 03; 17(3):511-524.

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Vishnevsky A, Savage MP, Fischman DL. Treatment of Clopidogrel Hypersensitivity: The Jefferson Approach. Curr Vasc Pharmacol. 2019; 17(2):123-126.

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Savage MP, Fischman DL. Clopidogrel Hypersensitivity: Overview of the Problem. Curr Vasc Pharmacol. 2019; 17(2):108-109.

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Whitley MJ, Henke DM, Ghazi A, Nieman M, Stoller M, Simon LM, Chen E, Vesci J, Holinstat M, McKenzie SE, Shaw CA, Edelstein LC, Bray PF. The protease-activated receptor?4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor?4 desensitization, and is blocked by non-competitive P2Y12 inhibition. J Thromb Haemost. 2018 12; 16(12):2501-2514.

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