"Porphyrias" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Descriptor ID |
D011164
|
| MeSH Number(s) |
C18.452.811
|
| Concept/Terms |
Porphyrias- Porphyrias
- Porphyrin Disorder
- Disorder, Porphyrin
- Disorders, Porphyrin
- Porphyrin Disorders
- Porphyria
|
Below are MeSH descriptors whose meaning is more general than "Porphyrias".
Below are MeSH descriptors whose meaning is more specific than "Porphyrias".
This graph shows the total number of publications written about "Porphyrias" by people in this website by year, and whether "Porphyrias" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Porphyrias" by people in Profiles.
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Frank J, McGrath J, Lam H, Graham RM, Hawk JL, Christiano AM. Homozygous variegate porphyria: identification of mutations on both alleles of the protoporphyrinogen oxidase gene in a severely affected proband. J Invest Dermatol. 1998 Apr; 110(4):452-5.
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Wakulchik SD, Schiltz JR, Bickers DR. Photolysis of protoporphyrin-treated human fibroblasts in vitro: studies on the mechanism. J Lab Clin Med. 1980 Jul; 96(1):158-67.
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Mathews-Roth MM, Abraham AA, Gabuzda TG. Beta-carotene content of certain organs from two patients receiving high doses of beta-carotene. Clin Chem. 1976 Jun; 22(6):922-4.
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Schreiner GE, Teehan BP. Dialysis of poisons and drugs--annual review. Trans Am Soc Artif Intern Organs. 1971; 17:513-44.