Procollagen N-Endopeptidase
"Procollagen N-Endopeptidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.
Descriptor ID |
D011348
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MeSH Number(s) |
D08.811.277.656.300.480.664 D08.811.277.656.675.374.664
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Concept/Terms |
Procollagen N-Endopeptidase- Procollagen N-Endopeptidase
- Procollagen N Endopeptidase
- Procollagen N-Proteinase
- Procollagen N Proteinase
- Procollagen Peptidase
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Below are MeSH descriptors whose meaning is more general than "Procollagen N-Endopeptidase".
Below are MeSH descriptors whose meaning is more specific than "Procollagen N-Endopeptidase".
This graph shows the total number of publications written about "Procollagen N-Endopeptidase" by people in this website by year, and whether "Procollagen N-Endopeptidase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Procollagen N-Endopeptidase" by people in Profiles.
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Wang J, Markova D, Anderson DG, Zheng Z, Shapiro IM, Risbud MV. TNF-a and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc. J Biol Chem. 2011 Nov 18; 286(46):39738-49.
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Majsterek I, McAdams E, Adachi E, Dhume ST, Fertala A. Prospects and limitations of the rational engineering of fibrillar collagens. Protein Sci. 2003 Sep; 12(9):2063-72.