"Proline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.
| Descriptor ID |
D011392
|
| MeSH Number(s) |
D12.125.072.401.623
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proline".
Below are MeSH descriptors whose meaning is more specific than "Proline".
This graph shows the total number of publications written about "Proline" by people in this website by year, and whether "Proline" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 3 | 5 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 4 | 5 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proline" by people in Profiles.
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Safiriyu AA, Mulchandani V, Anakkacheri MN, Pal D, Das Sarma J. Proline-Proline Dyad in the Fusion Peptide of the Murine ?-Coronavirus Spike Protein's S2 Domain Modulates Its Neuroglial Tropism. Viruses. 2023 Jan 12; 15(1).
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Masuda I, Yamaki Y, Detroja R, Tagore S, Moore H, Maharjan S, Nakano Y, Christian T, Matsubara R, Lowe TM, Frenkel-Morgenstern M, Hou YM. tRNA methylation resolves codon usage bias at the limit of cell viability. Cell Rep. 2022 10 25; 41(4):111539.
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Safiriyu AA, Singh M, Kishore A, Mulchandani V, Maity D, Behera A, Sinha B, Pal D, Das Sarma J. Two Consecutive Prolines in the Fusion Peptide of Murine ?-Coronavirus Spike Protein Predominantly Determine Fusogenicity and May Be Essential but Not Sufficient to Cause Demyelination. Viruses. 2022 04 17; 14(4).
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M?llhaupt B, Semela D, Ruckstuhl L, Magenta L, Clerc O, Torgler R, Negro F, Semmo N. Real-world effectiveness and safety of glecaprevir/pibrentasvir therapy in patients with chronic hepatitis C virus infection in Switzerland. Swiss Med Wkly. 2021 01 18; 151:w20399.
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Rout SS, Singh M, Shindler KS, Das Sarma J. One proline deletion in the fusion peptide of neurotropic mouse hepatitis virus (MHV) restricts retrograde axonal transport and neurodegeneration. J Biol Chem. 2020 05 15; 295(20):6926-6935.
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Gall AR, Datsenko KA, Figueroa-Bossi N, Bossi L, Masuda I, Hou YM, Csonka LN. Mg2+ regulates transcription of mgtA in Salmonella Typhimurium via translation of proline codons during synthesis of the MgtL peptide. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):15096-15101.
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Srivastava D, Zhu W, Johnson WH, Whitman CP, Becker DF, Tanner JJ. The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction. Biochemistry. 2010 Jan 26; 49(3):560-9.
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Mercier I, Bryant KG, Sotgia F, Bonuccelli G, Witkiewicz AK, Dasgupta A, Jasmin JF, Pestell RG, Lisanti MP. Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation. Cell Cycle. 2009 May 1; 8(9):1396-401.
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Evans BJ, Wang Z, Mobley L, Khosravi D, Fujii N, Navenot JM, Peiper SC. Physical association of GPR54 C-terminal with protein phosphatase 2A. Biochem Biophys Res Commun. 2008 Dec 26; 377(4):1067-71.
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Payne KE, Bray PF, Grant PJ, Carter AM. Beta3 integrin haplotype influences gene regulation and plasma von Willebrand factor activity. Atherosclerosis. 2008 Jun; 198(2):280-6.