"Complement Factor D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
Descriptor ID |
D011416
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MeSH Number(s) |
D08.811.277.300.450 D08.811.277.656.300.760.200 D08.811.277.656.959.350.200 D12.776.124.486.274.045.450
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Concept/Terms |
Complement Factor D- Complement Factor D
- Factor D, Complement
- C3PAse
- Complement Protein D
- Protein D, Complement
- GBGase
- Proactivator Convertase
- Convertase, Proactivator
- Properdin Factor D
- Factor D, Properdin
- C3 Proactivator Convertase
- Convertase, C3 Proactivator
- Adipsin
- C3 Convertase Activator
- Activator, C3 Convertase
- Convertase Activator, C3
- D Component of Complement
- Complement D Component
- 28 kDa Protein, Adipocyte
- C3PA Convertase
- Convertase, C3PA
- Factor D
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Below are MeSH descriptors whose meaning is more general than "Complement Factor D".
Below are MeSH descriptors whose meaning is more specific than "Complement Factor D".
This graph shows the total number of publications written about "Complement Factor D" by people in this website by year, and whether "Complement Factor D" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement Factor D" by people in Profiles.
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Yaspan BL, Williams DF, Holz FG, Regillo CD, Li Z, Dressen A, van Lookeren Campagne M, Le KN, Graham RR, Beres T, Bhangale TR, Honigberg LA, Smith A, Henry EC, Ho C, Strauss EC. Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration. Sci Transl Med. 2017 06 21; 9(395).
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Fain JN, Nesbit AS, Sudlow FF, Cheema P, Peeples JM, Madan AK, Tichansky DS. Release in vitro of adipsin, vascular cell adhesion molecule 1, angiotensin 1-converting enzyme, and soluble tumor necrosis factor receptor 2 by human omental adipose tissue as well as by the nonfat cells and adipocytes. Metabolism. 2007 Nov; 56(11):1583-90.