Retinoblastoma

"Retinoblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Descriptor ID	D012175
MeSH Number(s)	C04.557.465.625.600.725 C04.557.470.670.725 C04.557.580.625.600.725 C04.588.364.818.760 C11.319.475.760 C11.768.717.760
Concept/Terms	Retinoblastoma Retinoblastoma Retinoblastomas Neuroblastoma, Retinal Neuroblastomas, Retinal Retinal Neuroblastoma Retinal Neuroblastomas Glioma, Retinal Gliomas, Retinal Retinal Glioma Retinal Gliomas Eye Cancer, Retinoblastoma Glioblastoma, Retinal Glioblastomas, Retinal Retinal Glioblastoma Retinal Glioblastomas Sporadic Retinoblastoma Sporadic Retinoblastoma Retinoblastoma, Sporadic Retinoblastomas, Sporadic Sporadic Retinoblastomas Familial Retinoblastoma Familial Retinoblastoma Familial Retinoblastomas Retinoblastoma, Familial Retinoblastomas, Familial Hereditary Retinoblastoma Hereditary Retinoblastomas Retinoblastoma, Hereditary Retinoblastomas, Hereditary

Below are MeSH descriptors whose meaning is more general than "Retinoblastoma".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Germ Cell and Embryonal [C04.557.465]
Neuroectodermal Tumors [C04.557.465.625]
Neoplasms, Neuroepithelial [C04.557.465.625.600]
Retinoblastoma [C04.557.465.625.600.725]
Neoplasms, Glandular and Epithelial [C04.557.470]
Neoplasms, Neuroepithelial [C04.557.470.670]
Retinoblastoma [C04.557.470.670.725]
Neoplasms, Nerve Tissue [C04.557.580]
Neuroectodermal Tumors [C04.557.580.625]
Neoplasms, Neuroepithelial [C04.557.580.625.600]
Retinoblastoma [C04.557.580.625.600.725]
Neoplasms by Site [C04.588]
Eye Neoplasms [C04.588.364]
Retinal Neoplasms [C04.588.364.818]
Retinoblastoma [C04.588.364.818.760]
Eye Diseases [C11]
Eye Neoplasms [C11.319]
Retinal Neoplasms [C11.319.475]
Retinoblastoma [C11.319.475.760]
Retinal Diseases [C11.768]
Retinal Neoplasms [C11.768.717]
Retinoblastoma [C11.768.717.760]

Below are MeSH descriptors whose meaning is related to "Retinoblastoma".

Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Retinoblastoma" by people in this website by year, and whether "Retinoblastoma" was a major or minor topic of these publications.

Bar chart showing 101 publications over 22 distinct years, with a maximum of 9 publications in 2006 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	1	1
2002	6	0	6
2003	6	0	6
2004	7	0	7
2005	7	0	7
2006	9	0	9
2007	3	0	3
2008	3	0	3
2009	4	1	5
2010	7	0	7
2011	8	1	9
2012	5	1	6
2013	4	0	4
2014	4	0	4
2015	6	0	6
2016	4	0	4
2017	2	0	2
2018	1	0	1
2019	5	0	5
2020	1	0	1
2021	4	0	4
2022	1	0	1

Below are the most recent publications written about "Retinoblastoma" by people in Profiles.

Kaliki S, Shields CL, Cassoux N, Munier FL, Chantada G, Grossniklaus HE, Yoshikawa H, Fabian ID, Berry JL, McKenzie JD, Kimani K, Reddy MA, Parulekar M, Tanabe M, Furuta M, Grigorovski N, Chevez-Barrios P, Scanlan P, Eagle RC, Rashid R, Coronado RD, Sultana S, Staffieri S, Frenkel S, Suzuki S, Ushakova TL, Ji X. Defining High-risk Retinoblastoma: A Multicenter Global Survey. JAMA Ophthalmol. 2022 Jan 01; 140(1):30-36.

View in: PubMed
Shields CL, Shields JA. Here Comes the Sun ? for Retinoblastoma. Asia Pac J Ophthalmol (Phila). 2021 07 19; 10(4):341-342.

View in: PubMed
Shields CL, Dockery P, Ruben M, Yaghy A, Sunday MA, Duffner ER, Levin HJ, Taylor OS, Calotti M, Lally SE, Shields JA. Likelihood of Germline Mutation With Solitary Unilateral Retinoblastoma Based on Patient Age at Presentation: Analysis of 482 Consecutive Patients. J Pediatr Ophthalmol Strabismus. 2021 Nov-Dec; 58(6):355-364.

View in: PubMed
Shields CL, Srinivasan A, Lucio-Alvarez JA, Shields JA. Retinocytoma/retinoma: comparative analysis of clinical features in 78 tumors and rate of transformation into retinoblastoma over 20?years. J AAPOS. 2021 06; 25(3):147.e1-147.e8.

View in: PubMed
Shields CL, Dockery PW, Yaghy A, Duffner ER, Levin HJ, Taylor OS, Sajjadi Z, Lally SE, Shields JA, Rosenwasser R, Tjoumakaris S, Jabbour P. Intra-arterial chemotherapy for retinoblastoma in 341 consecutive eyes (1,292 infusions): comparative analysis of outcomes based on patient age, race, and sex. J AAPOS. 2021 06; 25(3):150.e1-150.e9.

View in: PubMed
Shields CL, Bas Z, Tadepalli S, Dalvin LA, Rao R, Schwendeman R, Lally SE, Shields JA, Shah A, Leahey A. Long-term (20-year) real-world outcomes of intravenous chemotherapy (chemoreduction) for retinoblastoma in 964 eyes of 554 patients at a single centre. Br J Ophthalmol. 2020 11; 104(11):1548-1555.

View in: PubMed
Ch?vez-Barrios P, Eagle RC, Krailo M, Piao J, Albert DM, Gao Y, Vemuganti G, Ali MJ, Khetan V, Honavar SG, O'Brien J, Leahey AM, Matthay K, Meadows A, Chintagumpala M. Study of Unilateral Retinoblastoma With and Without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy: A Children's Oncology Group Study. J Clin Oncol. 2019 11 01; 37(31):2883-2891.

View in: PubMed
Indovina P, Pentimalli F, Conti D, Giordano A. Translating RB1 predictive value in clinical cancer therapy: Are we there yet? Biochem Pharmacol. 2019 08; 166:323-334.

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Ravindran K, Dalvin LA, Pulido JS, Brinjikji W. Intra-arterial chemotherapy for retinoblastoma: an updated systematic review and meta-analysis. J Neurointerv Surg. 2019 Dec; 11(12):1266-1272.

View in: PubMed
Camp DA, Lally SE, Shields CL. Heterochromia following intravitreal chemotherapy in two cases. J AAPOS. 2019 08; 23(4):241-243.

View in: PubMed

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