"tRNA Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.
| Descriptor ID |
D012359
|
| MeSH Number(s) |
D08.811.913.555.500.925
|
| Concept/Terms |
tRNA Methyltransferases- tRNA Methyltransferases
- Methyltransferases, tRNA
- T RNA Methyltransferases
- Methyltransferases, T RNA
- RNA Methyltransferases, T
- RNA Methylases
- Methylases, RNA
- RNA, Transfer, Methyltransferases
|
Below are MeSH descriptors whose meaning is more general than "tRNA Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "tRNA Methyltransferases".
This graph shows the total number of publications written about "tRNA Methyltransferases" by people in this website by year, and whether "tRNA Methyltransferases" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 3 | 0 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "tRNA Methyltransferases" by people in Profiles.
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Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE, Svidritskiy E, Hou YM, Korostelev AA. Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun. 2021 07 30; 12(1):4644.
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Masuda I, Matsubara R, Christian T, Rojas ER, Yadavalli SS, Zhang L, Goulian M, Foster LJ, Huang KC, Hou YM. tRNA Methylation Is a Global Determinant of Bacterial Multi-drug Resistance. Cell Syst. 2019 04 24; 8(4):302-314.e8.
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Hou YM, Matsubara R, Takase R, Masuda I, Sulkowska JI. TrmD: A Methyl Transferase for tRNA Methylation With m1G37. Enzymes. 2017; 41:89-115.
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Gall AR, Datsenko KA, Figueroa-Bossi N, Bossi L, Masuda I, Hou YM, Csonka LN. Mg2+ regulates transcription of mgtA in Salmonella Typhimurium via translation of proline codons during synthesis of the MgtL peptide. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):15096-15101.
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Christian T, Sakaguchi R, Perlinska AP, Lahoud G, Ito T, Taylor EA, Yokoyama S, Sulkowska JI, Hou YM. Methyl transfer by substrate signaling from a knotted protein fold. Nat Struct Mol Biol. 2016 Oct; 23(10):941-948.
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Hou YM. Single-Turnover Kinetics of Methyl Transfer to tRNA by Methyltransferases. Methods Mol Biol. 2016; 1421:79-96.
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Ito T, Masuda I, Yoshida K, Goto-Ito S, Sekine S, Suh SW, Hou YM, Yokoyama S. Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD. Proc Natl Acad Sci U S A. 2015 Aug 04; 112(31):E4197-205.
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Hou YM, Masuda I. Kinetic Analysis of tRNA Methyltransferases. Methods Enzymol. 2015; 560:91-116.
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Sakaguchi R, Lahoud G, Christian T, Gamper H, Hou YM. A divalent metal ion-dependent N(1)-methyl transfer to G37-tRNA. Chem Biol. 2014 Oct 23; 21(10):1351-1360.
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Masuda I, Sakaguchi R, Liu C, Gamper H, Hou YM. The temperature sensitivity of a mutation in the essential tRNA modification enzyme tRNA methyltransferase D (TrmD). J Biol Chem. 2013 Oct 04; 288(40):28987-96.