Substance Withdrawal Syndrome

"Substance Withdrawal Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Descriptor ID	D013375
MeSH Number(s)	C25.775.835 F03.900.825
Concept/Terms	Substance Withdrawal Syndrome Substance Withdrawal Syndrome Substance Withdrawal Syndromes Syndrome, Substance Withdrawal Syndromes, Substance Withdrawal Withdrawal Syndrome, Substance Withdrawal Syndromes, Substance Withdrawal Symptoms Withdrawal Symptoms Symptom, Withdrawal Symptoms, Withdrawal Withdrawal Symptom Drug Withdrawal Symptoms Drug Withdrawal Symptoms Drug Withdrawal Symptom Symptom, Drug Withdrawal Symptoms, Drug Withdrawal Withdrawal Symptom, Drug Withdrawal Symptoms, Drug

Below are MeSH descriptors whose meaning is more general than "Substance Withdrawal Syndrome".

Diseases [C]
Chemically-Induced Disorders [C25]
Substance-Related Disorders [C25.775]
Substance Withdrawal Syndrome [C25.775.835]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Substance-Related Disorders [F03.900]
Substance Withdrawal Syndrome [F03.900.825]

Below are MeSH descriptors whose meaning is related to "Substance Withdrawal Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Substance Withdrawal Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Substance Withdrawal Syndrome" by people in this website by year, and whether "Substance Withdrawal Syndrome" was a major or minor topic of these publications.

Bar chart showing 72 publications over 26 distinct years, with a maximum of 8 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	0	3
1997	3	0	3
2000	1	0	1
2002	1	2	3
2003	2	1	3
2004	1	0	1
2005	1	2	3
2006	3	0	3
2007	0	1	1
2008	3	1	4
2009	1	1	2
2010	2	1	3
2011	1	2	3
2012	5	3	8
2013	1	2	3
2014	3	0	3
2015	1	0	1
2016	2	1	3
2017	0	1	1
2018	2	2	4
2019	1	1	2
2021	2	0	2
2022	5	0	5
2023	3	0	3
2024	2	1	3
2025	1	0	1

Below are the most recent publications written about "Substance Withdrawal Syndrome" by people in Profiles.

Lam K, Peltz G, Kraft WK. The role of 5-HT modulation in opioid withdrawal and neonatal opioid withdrawal syndrome: mechanisms and potential serotonergic targets. Expert Opin Investig Drugs. 2025 Jan-Feb; 34(1-2):49-59.

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Reed MK, Esteves Camacho T, Olson R, Grover Z, Rapoza T, Larson MJ. Xylazine's Impacts on the Community in Philadelphia: Perspectives of People Who Use Opioids and Harm Reduction Workers. Subst Use Misuse. 2025; 60(1):100-107.

View in: PubMed
London K, Li Y, Kahoud JL, Cho D, Mulholland J, Roque S, Stugart L, Gillingham J, Borne E, Slovis B. Tranq Dope: Characterization of an ED cohort treated with a novel opioid withdrawal protocol in the era of fentanyl/xylazine. Am J Emerg Med. 2024 Nov; 85:130-139.

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Iyer NS, Ferguson EB, Yan VZ, Hand DJ, Abatemarco DJ, Boelig RC. Standard Versus Rapid Inpatient Methadone Titration for Pregnant Patients With Opioid Use Disorder: A Retrospective Cohort Study. J Addict Med. 2024 Nov-Dec 01; 18(6):670-674.

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Stern SJ, D'Orazio JL, Work BD, Calcaterra SL, Thakrar AP. Point/counterpoint: Should full agonist opioid medications be offered to hospitalized patients for management of opioid withdrawal? J Hosp Med. 2024 04; 19(4):339-343.

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Quezada M, Ponce C, Berr?os-C?rcamo P, Santapau D, Gallardo J, De Gregorio C, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M, Israel Y, Andr?s-Herrera P, Hip?lito L, Ezquer F. Amelioration of morphine withdrawal syndrome by systemic and intranasal administration of mesenchymal stem cell-derived secretome in preclinical models of morphine dependence. CNS Neurosci Ther. 2024 04; 30(4):e14517.

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Young LW, Ounpraseuth ST, Merhar SL, Hu Z, Simon AE, Bremer AA, Lee JY, Das A, Crawford MM, Greenberg RG, Smith PB, Poindexter BB, Higgins RD, Walsh MC, Rice W, Paul DA, Maxwell JR, Telang S, Fung CM, Wright T, Reynolds AM, Hahn DW, Ross J, McAllister JM, Crowley M, Shaikh SK, Puopolo KM, Christ L, Brown J, Riccio J, Wong Ramsey K, Braswell EF, Tucker L, McAlmon KR, Dummula K, Weiner J, White JR, Howell MP, Newman S, Snowden JN, Devlin LA. Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal. N Engl J Med. 2023 06 22; 388(25):2326-2337.

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Quintanilla ME, Quezada M, Morales P, Berr?os-C?rcamo P, Santapau D, Ezquer M, Herrera-Marschitz M, Israel Y, Ezquer F. Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence. Transl Psychiatry. 2022 11 04; 12(1):462.

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Polintan ETT, Danganan LML, Cruz NS, Macapagal SC, Catahay JA, Patarroyo-Aponte G, Azmaiparashvili Z, Lo KB. Adjunctive Dexmedetomidine in Alcohol Withdrawal Syndrome: A Systematic Review and Meta-analysis of Retrospective Cohort Studies and Randomized Controlled Trials. Ann Pharmacother. 2023 06; 57(6):696-705.

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Zavodnick J, Heinsinger NM, Lepore AC, Sterling RC. Medication Initiation, Patient-directed Discharges, and Hospital Readmissions Before and After Implementing Guidelines for Opioid Withdrawal Management. J Addict Med. 2023 Jan-Feb 01; 17(1):e57-e63.

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