"Tacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
| Descriptor ID |
D013619
|
| MeSH Number(s) |
D03.633.300.046.250.900
|
| Concept/Terms |
Tacrine- Tacrine
- 9-Amino-1,2,3,4-Tetrahydroacridine
- 1,2,3,4-Tetrahydro-9-acridinamine
- Tetrahydroaminoacridine
- 1,2,3,4-Tetrahydroaminoacridine
|
Below are MeSH descriptors whose meaning is more general than "Tacrine".
Below are MeSH descriptors whose meaning is more specific than "Tacrine".
This graph shows the total number of publications written about "Tacrine" by people in this website by year, and whether "Tacrine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tacrine" by people in Profiles.
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Qaseem A, Snow V, Cross JT, Forciea MA, Hopkins R, Shekelle P, Adelman A, Mehr D, Schellhase K, Campos-Outcalt D, Santaguida P, Owens DK. Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Ann Intern Med. 2008 Mar 04; 148(5):370-8.
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Zarowitz BJ, Stefanacci R, Hollenack K, O'Shea T, Gruber J, Tangalos EG. The application of evidence-based principles of care in older persons (issue 5): Alzheimer's disease. J Am Med Dir Assoc. 2007 Mar; 8(3):183-93.
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Zhang W, Johnson BR, Bjornsson TD. Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid beta-peptide. Life Sci. 1997; 60(25):2323-32.