Drug Interactions

"Drug Interactions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The action of a drug that may affect the activity, metabolism, or toxicity of another drug.

Descriptor ID	D004347
MeSH Number(s)	G07.690.773.968
Concept/Terms	Drug Interactions Drug Interactions Drug Interaction Interaction, Drug Interactions, Drug

Below are MeSH descriptors whose meaning is more general than "Drug Interactions".

Biological Sciences [G]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacological Phenomena [G07.690.773]
Drug Interactions [G07.690.773.968]

Below are MeSH descriptors whose meaning is related to "Drug Interactions".

Below are MeSH descriptors whose meaning is more specific than "Drug Interactions".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Interactions" by people in this website by year, and whether "Drug Interactions" was a major or minor topic of these publications.

Bar chart showing 115 publications over 29 distinct years, with a maximum of 9 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	3	3
1997	0	2	2
1998	0	2	2
1999	0	3	3
2000	1	5	6
2001	1	1	2
2002	0	6	6
2003	2	5	7
2004	0	5	5
2005	0	4	4
2006	1	6	7
2007	0	3	3
2008	0	3	3
2009	0	2	2
2010	0	9	9
2011	0	2	2
2012	0	8	8
2013	0	2	2
2014	1	2	3
2015	0	5	5
2016	1	5	6
2017	1	6	7
2018	1	7	8
2019	1	1	2
2020	0	2	2
2022	0	3	3
2023	0	1	1
2024	0	1	1
2025	0	1	1

Below are the most recent publications written about "Drug Interactions" by people in Profiles.

Kugelman DN, Leal J, Shah S, Wrenn R, Mackowiak A, Ryan SP, Jiranek WA, Seyler TM, Seidelman J. How Often Is Rifampin Therapy Initiated and Completed in Patients With Periprosthetic Joint Infections? Clin Orthop Relat Res. 2025 01 23; 483(7):1215-1221.

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Huestis MA, Smith WB, Leonowens C, Blanchard R, Viaccoz A, Spargo E, Miner NB, Yazar-Klosinski B. MDMA pharmacokinetics: A population and physiologically based pharmacokinetics model-informed analysis. CPT Pharmacometrics Syst Pharmacol. 2025 02; 14(2):376-388.

View in: PubMed
Shore N, Garcia-Horton V, Terasawa E, Ayyagari R, Grossman JP, Waldeck AR. Safety differences across androgen receptor inhibitors in nonmetastatic castration-resistant prostate cancer. Future Oncol. 2023 Feb; 19(5):385-395.

View in: PubMed
Van den Eynde V, Abdelmoemin WR, Abraham MM, Amsterdam JD, Anderson IM, Andrade C, Baker GB, Beekman ATF, Berk M, Birkenh?ger TK, Blackwell BB, Blier P, Blom MBJ, Bodkin AJ, Cattaneo CI, Dantz B, Davidson J, Dunlop BW, Est?vez RF, Feinberg SS, Finberg JPM, Fochtmann LJ, Gotlib D, Holt A, Insel TR, Larsen JK, Mago R, Menkes DB, Meyer JM, Nutt DJ, Parker G, Rego MD, Richelson E, Ruh? HG, S?iz-Ruiz J, Stahl SM, Steele T, Thase ME, Ulrich S, van Balkom AJLM, Vieta E, Whyte I, Young AH, Gillman PK. The prescriber's guide to classic MAO inhibitors (phenelzine, tranylcypromine, isocarboxazid) for treatment-resistant depression. CNS Spectr. 2023 08; 28(4):427-440.

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Mar PL, Gopinathannair R, Gengler BE, Chung MK, Perez A, Dukes J, Ezekowitz MD, Lakkireddy D, Lip GYH, Miletello M, Noseworthy PA, Reiffel J, Tisdale JE, Olshansky B. Drug Interactions Affecting Oral Anticoagulant Use. Circ Arrhythm Electrophysiol. 2022 06; 15(6):e007956.

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Mar PL, Horbal P, Chung MK, Dukes JW, Ezekowitz M, Lakkireddy D, Lip GYH, Miletello M, Noseworthy PA, Reiffel JA, Tisdale JE, Olshansky B, Gopinathannair R. Drug Interactions Affecting Antiarrhythmic Drug Use. Circ Arrhythm Electrophysiol. 2022 05; 15(5):e007955.

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Morgans AK, Shore N, Cope D, McNatty A, Moslehi J, Gomella L, Sartor O. Androgen receptor inhibitor treatments: Cardiovascular adverse events and comorbidity considerations in patients with non-metastatic prostate cancer. Urol Oncol. 2021 01; 39(1):52-62.

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Lam E, Schaefer J, Zheng R, Zhan T, Kraft WK. Twice-Daily Doravirine Overcomes the Interaction Effect from Once-Weekly Rifapentine and Isoniazid in Healthy Volunteers. Clin Transl Sci. 2020 11; 13(6):1244-1250.

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Shore N, Zurth C, Fricke R, Gieschen H, Graudenz K, Koskinen M, Ploeger B, Moss J, Prien O, Borghesi G, Petrenciuc O, Tammela TL, Kuss I, Verholen F, Smith MR, Fizazi K. Evaluation of Clinically Relevant Drug-Drug Interactions and Population Pharmacokinetics of Darolutamide in Patients with Nonmetastatic Castration-Resistant Prostate Cancer: Results of Pre-Specified and Post Hoc Analyses of the Phase III ARAMIS Trial. Target Oncol. 2019 10; 14(5):527-539.

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Moadel D, Chism K. Medical Marijuana-Induced Tacrolimus Toxicity. Psychosomatics. 2019 Nov - Dec; 60(6):603-605.

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