Tissue Distribution

"Tissue Distribution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.

Descriptor ID	D014018
MeSH Number(s)	G03.787.917 G07.690.725.949
Concept/Terms	Tissue Distribution Tissue Distribution Distribution, Tissue Distributions, Tissue Tissue Distributions

Below are MeSH descriptors whose meaning is more general than "Tissue Distribution".

Biological Sciences [G]
Metabolism [G03]
Pharmacokinetics [G03.787]
Tissue Distribution [G03.787.917]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacokinetics [G07.690.725]
Tissue Distribution [G07.690.725.949]

Below are MeSH descriptors whose meaning is related to "Tissue Distribution".

Below are MeSH descriptors whose meaning is more specific than "Tissue Distribution".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tissue Distribution" by people in this website by year, and whether "Tissue Distribution" was a major or minor topic of these publications.

Bar chart showing 226 publications over 28 distinct years, with a maximum of 20 publications in 2002

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1996	8	8
1997	11	11
1998	5	5
1999	18	18
2000	12	12
2001	13	13
2002	20	20
2003	8	8
2004	9	9
2005	8	8
2006	11	11
2007	13	13
2008	5	5
2009	13	13
2010	11	11
2011	7	7
2012	8	8
2013	6	6
2014	5	5
2015	7	7
2016	8	8
2017	2	2
2018	3	3
2019	1	1
2020	7	7
2021	5	5
2022	1	1
2023	1	1

Below are the most recent publications written about "Tissue Distribution" by people in Profiles.

Kommineni N, Chaudhari R, Conde J, Tamburaci S, Cecen B, Chandra P, Prasad R. Engineered Liposomes in Interventional Theranostics of Solid Tumors. ACS Biomater Sci Eng. 2023 08 14; 9(8):4527-4557.

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Lacerda Q, Rochani A, Oeffinger B, Liu JB, Wessner CE, Tahmasebi A, Falatah H, Lee P, Leeper DB, Forsberg F, Curry J, Keith SW, O'Kane P, Kaushal G, Wheatley MA, Eisenbrey JR. Tumoral oxygenation and biodistribution of Lonidamine oxygen microbubbles following localized ultrasound-triggered delivery. Int J Pharm. 2022 Sep 25; 625:122072.

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Tuv SS, Bergh MS, Andersen JM, Steinsland S, Vindenes V, Baumann MH, Huestis MA, Bogen IL. Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents. Int J Mol Sci. 2021 Nov 05; 22(21).

View in: PubMed
Richter H, B?cker P, Martin LF, Dunker C, Fingerhut S, Xia A, Karol A, Sperling M, Karst U, Radbruch A, Jeibmann A. Gadolinium Tissue Distribution in a Large-Animal Model after a Single Dose of Gadolinium-based Contrast Agents. Radiology. 2021 12; 301(3):637-642.

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Burashnikov A, Barajas-Martinez H, Cox R, Demitrack MA, Fossler MJ, Kramer M, Kleiman RB, Kowey P, Antzelevitch C. Intracellular uptake of agents that block the hERG channel can confound the assessment of QT interval prolongation and arrhythmic risk. Heart Rhythm. 2021 12; 18(12):2177-2186.

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Bitting RL, Tooze JA, Isom S, Petty WJ, Grant SC, Desnoyers RJ, Thomas A, Thomas CY, Alistar AT, Golden SL, Pleasant K, Chappell MC, Tallant EA, Gallagher PE, Klepin HD. Phase I Study of Muscadine?Grape Extract for Patients With Advanced Cancer. Am J Clin Oncol. 2021 06 01; 44(6):239-246.

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Safary A, Moghaddas-Sani H, Akbarzadeh-Khiavi M, Khabbazzi A, Rafi MA, Omidi Y. Enzyme replacement combinational therapy: effective treatments for mucopolysaccharidoses. Expert Opin Biol Ther. 2021 09; 21(9):1181-1197.

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Yee K, Papayannidis C, Vey N, Dickinson MJ, Kelly KR, Assouline S, Kasner M, Seiter K, Drummond MW, Yoon SS, Lee JH, Blotner S, Jukofsky L, Pierceall WE, Zhi J, Simon S, Higgins B, Nichols G, Monnet A, Muehlbauer S, Ott M, Chen LC, Martinelli G. Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study?. Leuk Res. 2021 01; 100:106489.

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Jacobs SA, Lee JJ, George TJ, Wade JL, Stella PJ, Wang D, Sama AR, Piette F, Pogue-Geile KL, Kim RS, Gavin PG, Lipchik C, Feng H, Wang Y, Finnigan M, Kiesel BF, Beumer JH, Wolmark N, Lucas PC, Allegra CJ, Srinivasan A. Neratinib-Plus-Cetuximab in Quadruple-WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study. Clin Cancer Res. 2021 03 15; 27(6):1612-1622.

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Torrens A, Vozella V, Huff H, McNeil B, Ahmed F, Ghidini A, Mahler SV, Huestis MA, Das A, Piomelli D. Comparative Pharmacokinetics of ?9-Tetrahydrocannabinol in Adolescent and Adult Male Mice. J Pharmacol Exp Ther. 2020 07; 374(1):151-160.

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