Pawan Sharma

TitleInstructor
InstitutionThomas Jefferson University
DepartmentCenter for Translational Medic
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sharma P, Alizadeh J, Juarez M, Samali A, Halayko AJ, Kenyon NJ, Ghavami S, Zeki AA. Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis. Cells. 2021 Jun 30; 10(7). PMID: 34209019.
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    2. Seyfoori A, Shokrollahi Barough M, Mokarram P, Ahmadi M, Mehrbod P, Sheidary A, Madrakian T, Kiumarsi M, Walsh T, McAlinden KD, Ghosh CC, Sharma P, Zeki AA, Ghavami S, Akbari M. Emerging Advances of Nanotechnology in Drug and Vaccine Delivery against Viral Associated Respiratory Infectious Diseases (VARID). Int J Mol Sci. 2021 Jun 28; 22(13). PMID: 34203268.
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    3. Naidu V, Zeki AA, Sharma P. Sex differences in the induction of angiotensin converting enzyme 2 (ACE-2) in mouse lungs after e-cigarette vapor exposure and its relevance to COVID-19. J Investig Med. 2021 Apr 29. PMID: 33926967.
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    4. Sharma P, Conaway S, Deshpande D. Bitter Taste Receptors in the Airway Cells Functions. Handb Exp Pharmacol. 2021 Feb 19. PMID: 33604702.
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    5. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. PMID: 33634751.
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    6. Sharma P, McAlinden KD, Ghavami S, Deshpande DA. Chloroquine: Autophagy inhibitor, antimalarial, bitter taste receptor agonist in fight against COVID-19, a reality check? Eur J Pharmacol. 2021 Apr 15; 897:173928. PMID: 33545161.
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    7. Peymani P, Dehesh T, Aligolighasemabadi F, Sadeghdoust M, Kotfis K, Ahmadi M, Mehrbod P, Iranpour P, Dastghaib S, Nasimian A, Ravandi A, Kidane B, Ahmed N, Sharma P, Shojaei S, Bagheri Lankarani K, Madej A, Rezaei N, Madrakian T, Los MJ, Labouta HI, Mokarram P, Ghavami S. Statins in patients with COVID-19: a retrospective cohort study in Iranian COVID-19 patients. Transl Med Commun. 2021; 6(1):3. PMID: 33521322.
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    8. Thimmuri D, P A S, N P S, Khan A, Gawali B, Rajdev B, Adhikari C, V R, Sharma P, Naidu V. Hispolon inhibits RANKL induced osteoclast differentiation in vitro. Immunol Lett. 2021 Mar; 231:35-42. PMID: 33428992.
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    9. Dastghaib S, Kumar PS, Aftabi S, Damera G, Dalvand A, Sepanjnia A, Kiumarsi M, Aghanoori MR, Sohal SS, Ande SR, Alizadeh J, Mokarram P, Ghavami S, Sharma P, Zeki AA. Mechanisms Targeting the Unfolded Protein Response in Asthma. Am J Respir Cell Mol Biol. 2021 Jan; 64(1):29-38. PMID: 32915643.
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    10. Aghaei M, Dastghaib S, Aftabi S, Aghanoori MR, Alizadeh J, Mokarram P, Mehrbod P, Ashrafizadeh M, Zarrabi A, McAlinden KD, Eapen MS, Sohal SS, Sharma P, Zeki AA, Ghavami S. The ER Stress/UPR Axis in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis. Life (Basel). 2020 Dec 22; 11(1). PMID: 33374938.
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    11. Dastghaib S, Shojaei S, Mostafavi-Pour Z, Sharma P, Patterson JB, Samali A, Mokarram P, Ghavami S. Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells. Cells. 2020 10 22; 9(11). PMID: 33105603.
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    12. Sharma P, Zeki AA. Does Vaping Increase Susceptibility to COVID-19? Am J Respir Crit Care Med. 2020 Aug 04. PMID: 32749868.
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    13. McAlinden KD, Eapen MS, Lu W, Sharma P, Sohal SS. The Ill Effects of IQOS on Airway Cells: Let's Not Get Burned All Over Again. Am J Respir Cell Mol Biol. 2020 08; 63(2):269-270. PMID: 32735165.
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    14. McAlinden KD, Eapen MS, Lu W, Sharma P, Sohal SS. The rise of electronic nicotine delivery systems and the emergence of electronic-cigarette-driven disease. Am J Physiol Lung Cell Mol Physiol. 2020 10 01; 319(4):L585-L595. PMID: 32726146.
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    15. McAlinden KD, Kota A, Haghi M, Ghavami S, Sharma P. Pharmacologic Inhibition of Vacuolar H+ATPase Attenuates Features of Severe Asthma in Mice. Am J Respir Cell Mol Biol. 2020 01; 62(1):117-120. PMID: 31891310.
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    16. McAlinden KD, Eapen MS, Ghavami S, Sohal SS, Sharma P. Altered Calcium in Ciliary Dysfunction: Potential Role of Endoplasmic Reticulum Stress and Ciliophagy. Am J Respir Cell Mol Biol. 2019 Dec;61(6):794-795. doi: 10.1165/rcmb.2019-0157LE. PubMed PMID: 31774335. 2019.
    17. Eapen MS, Sharma P, Thompson IE, Lu W, Myers S, Hansbro PM, Sohal SS. Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies. Lab Invest. 2019 Feb;99(2):150-157. doi: 10.1038/s41374-018-0146-0. Epub 2018 Nov 19. Review. PubMed PMID: 30451982. 2019.
    18. Eapen MS, Sharma P, Sohal SS. Mitochondrial dysfunction in macrophages: a key to defective bacterial phagocytosis in COPD. Eur Respir J. 2019 Oct;54(4). doi: 10.1183/13993003.01641-2019. Print 2019 Oct. PubMed PMID: 31601722. 2019.
    19. Emami A, Shojaei S, da Silva Rosa SC, Aghaei M, Samiei E, Vosoughi AR, Kalantari F, Kawalec P, Thliveris J, Sharma P, Zeki AA, Akbari M, Gordon JW, Ghavami S. Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition. Eur J Pharmacol. 2019 Nov 5;862:172616. doi: 10.1016/j.ejphar.2019.172616. Epub 2019 Aug 23. PubMed PMID: 31449810. 2019.
    20. McAlinden KD, Sohal SS, Sharma P. There can be smoke without fire: warranted caution in promoting electronic cigarettes and heat not burn devices as a safer alternative to cigarette smoking. ERJ Open Res. 2019 Jul;5(3). doi: 10.1183/23120541.00114-2019. eCollection 2019 Jul. PubMed PMID: 31423449; PubMed Central PMCID: PMC6689670. 2019.
    21. Eapen MS, Sharma P, Gaikwad AV, Lu W, Myers S, Hansbro PM, Sohal SS. Epithelial-mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics. Int J Chron Obstruct Pulmon Dis. 2019;14:1603-1610. doi: 10.2147/COPD.S208428. eCollection 2019. PubMed PMID: 31409985; PMCID: PMC6645357. 2019.
    22. Atto B, Eapen MS, Sharma P, Frey U, Ammit AJ, Markos J, Chia C, Larby J, Haug G, Weber HC, Mabeza G, Tristram S, Myers S, Geraghty DP, Flanagan KL, Hansbro PM, Sohal SS. New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways. Clin Sci (Lond). 2019 Jul 31;133(14):1663-1703. doi: 10.1042/CS20181009.PubMed PMID: 31346069. 2019.
    23. Lu W, Sharma P, Eapen MS, Sohal SS . Inhaled corticosteroids attenuate epithelial mesenchymal transition: implications for COPD and lung cancer prophylaxis. Eur Respir J. 2019 Jul;54(1). doi: 10.1183/13993003.00778-2019. Print 2019 Jul. PubMed PMID: 31296782. 2019.
    24. Eapen MS, Gaikwad AV, Thompson IE, Lu W, Myers S, Sharma P, Sohal SS. The effectiveness of immunosuppressive cyclosporin in attenuating the progression of interstitial lung diseases. J Thorac Dis. 2019 May;11(Suppl 9):S1139-S1142. doi: 10.21037/jtd.2019.04.44. PubMed PMID: 31245065; PubMed Central PMCID: PMC6560594. 2019.
    25. Sohal SS, Eapen MS, Naidu VGM, Sharma P. IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette. ERJ Open Res. 2019; 1(5). View Publication.
    26. Eapen MS, Sharma P, Thompson IE, Lu W, Myers S, Hansbro PM, Sohal SS. Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies. Lab Invest. 2019 02; 99(2):150-157. PMID: 30451982.
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    27. Saha P, Johny E, Dangi A, Shinde S, Brake S, Eapen MS, Sohal SS, Naidu V, Sharma P . Impact of Maternal Air Pollution Exposure on Children's Lung Health: An Indian Perspective. Toxics. 2018 Nov 16;6(4). doi: 10.3390/toxics6040068. Review. PubMed PMID: 30453488; PubMed Central PMCID: PMC6315719. 2018.
    28. Eapen MS, Hansbro PM, Larsson-Callerfelt AK, Jolly MK, Myers S, Sharma P, Jones B, Rahman MA, Markos J, Chia C, Larby J, Haug G, Hardikar A, Weber HC, Mabeza G, Cavalheri V, Khor YH, McDonald CF, Sohal SS . Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities. Drugs. 2018 Nov;78(16):1717-1740. doi: 10.1007/s40265-018-1001-8. Review. PubMed PMID: 30392114. 2018.
    29. McAlinden KD, Deshpande DA, Ghavami S, Xenaki D, Sohal SS, Oliver BG, Haghi M, Sharma P. Autophagy Activation in Asthma Airways Remodeling. Am J Respir Cell Mol Biol. 2018 Nov 01. PMID: 30383396.
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    30. Tonga KO, King GG, Farah CS, Thamrin C, Tang FS, Santos J, Sharma P, Chapman DG, Oliver BG . Steroid insensitive fixed airflow obstruction is not related to airway inflammation in older non-smokers with asthma. Respir Res. 2018 Sep 17;19(1):176. doi: 10.1186/s12931-018-0880-2. PubMed PMID: 30223904; PubMed Central PMCID: PMC6142701. 2018.
    31. Eapen MS, Kota A, Vindin H, McAlinden KD, Xenaki D, Oliver BG, Deshpande DA, Sohal SS, Sharma P. Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease. Clin Sci (Lond). 2018 Jul 31; 132(14):1615-1627. PMID: 30006481.
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    32. Eapen MS, Myers S, Lu W, Tanghe C, Sharma P, Sohal SS . sE-cadherin and sVE-cadherin indicate active epithelial/endothelial to mesenchymal transition (EMT and EndoMT) in smokers and COPD: implications for new biomarkers and therapeutics. Biomarkers. 2018 Nov;23(7):709-711. doi: 10.1080/1354750X.2018.1479772. Epub 2018 Jun 19. PubMed PMID: 29781727. 2018.
    33. Chen H, Li G, Chan YL, Chapman DG, Sukjamnong S, Nguyen T, Annissa T, McGrath KC, Sharma P, Oliver BG. Maternal E-Cigarette Exposure in Mice Alters DNA Methylation and Lung Cytokine Expression in Offspring. Am J Respir Cell Mol Biol. 2018 03; 58(3):366-377. PMID: 28960086.
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    34. Comas M, Gordon CJ, Oliver BG, Stow NW, King G, Sharma P, Ammit AJ, Grunstein RR, Phillips CL . A circadian based inflammatory response – implications for respiratory disease and treatment. Sleep Science and Practice. 2017 December; 1(18). doi: 10.1186/s41606-017-0019-2. 2017.
    35. Sukjamnong S, Chan YL, Zakarya R, Saad S, Sharma P, Santiyanont R, Chen H, Oliver BG. Effect of long-term maternal smoking on the offspring's lung health. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L416-L423. PMID: 28522560.
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    36. Pan S, Sharma P, Shah SD, Deshpande DA. Bitter taste receptor agonists alter mitochondrial function and induce autophagy in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2017 Jul 01; 313(1):L154-L165. PMID: 28450286.
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    37. Sharma P, Yi R, Nayak AP, Wang N, Tang F, Knight MJ, Pan S, Oliver B, Deshpande DA. Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice. Sci Rep. 2017 Apr 11; 7:46166. PMID: 28397820.
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    38. Kota A, Deshpande D, Haghi M, Oliver B, Sharma P. Autophagy and airway fibrosis: Is there a link? F1000Res. 2017; 6:409. PMID: 28815017.
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    39. Sharma P, Panebra A, Pera T, Tiegs BC, Hershfeld A, Kenyon LC, Deshpande DA. Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2016 Feb 15; 310(4):L365-76. PMID: 26684251.
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    40. Sharma P, Jha A, Stelmack GL, Detillieux K, Basu S, Klonisch T, Unruh H, Halayko AJ . Characterization of the dystrophin-glycoprotein complex in airway smooth muscle: role of d-sarcoglycan in airway responsiveness. Can J Physiol Pharmacol. 2015 Mar;93(3):195-202. doi: 10.1139/cjpp-2014-0389. Epub 2015 Jan 14. PubMed PMID: 25692961. 2015.
    41. Jha A, Sharma P, Anaparti V, Ryu MH, Halayko AJ. A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness? Can J Physiol Pharmacol. 2015 Mar; 93(3):171-6. PMID: 25654580.
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    42. Boardman C, Chachi L, Gavrila A, Keenan CR, Perry MM, Xia YC, Meurs H, Sharma P . Mechanisms of glucocorticoid action and insensitivity in airways disease. Pulm Pharmacol Ther. 2014 Dec;29(2):129-43. doi: 10.1016/j.pupt.2014.08.008. Epub 2014 Sep 9. Review. PubMed PMID: 25218650. 2014.
    43. Sharma P, Basu S, Mitchell RW, Stelmack GL, Anderson JE, Halayko AJ. Role of dystrophin in airway smooth muscle phenotype, contraction and lung function. PLoS One. 2014; 9(7):e102737. PMID: 25054970.
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    44. Ghavami S, Sharma P, Yeganeh B, Ojo OO, Jha A, Mutawe MM, Kashani HH, Los MJ, Klonisch T, Unruh H, Halayko AJ . Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins. Biochim Biophys Acta. 2014 Jul;1843(7):1259-71. doi: 10.1016/j.bbamcr.2014.03.006. Epub 2014 Mar 15. PubMed PMID: 24637330. 2014.
    45. Yeganeh B, Wiechec E, Ande SR, Sharma P, Moghadam AR, Post M, Freed DH, Hashemi M, Shojaei S, Zeki AA, Ghavami S . Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. Pharmacol Ther. 2014 Jul;143(1):87-110. doi: 10.1016/j.pharmthera.2014.02.007. Epub 2014 Feb 26. Review. PubMed PMID: 24582968; PubMed Central PMCID: PMC4005604. 2014.
    46. Ghavami S, Sharma P, Yeganeh B, Ojo OO, Jha A, Mutawe MM, Kashani HH, Los MJ, Klonisch T, Unruh H, Halayko AJ. Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins. Biochim Biophys Acta. 2014 Jul; 1843(7):1259-71. PMID: 24637330.
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    47. Yeganeh B, Wiechec E, Ande SR, Sharma P, Moghadam AR, Post M, Freed DH, Hashemi M, Shojaei S, Zeki AA, Ghavami S. Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. Pharmacol Ther. 2014 Jul; 143(1):87-110. PMID: 24582968.
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    48. Moodley T, Wilson SM, Joshi T, Rider CF, Sharma P, Yan D, Newton R, Giembycz MA. Phosphodiesterase 4 inhibitors augment the ability of formoterol to enhance glucocorticoid-dependent gene transcription in human airway epithelial cells: a novel mechanism for the clinical efficacy of roflumilast in severe chronic obstructive pulmonary disease. Mol Pharmacol. 2013 Apr; 83(4):894-906. PMID: 23389862.
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    49. Sharma P, Ryu MH, Basu S, Maltby SA, Yeganeh B, Mutawe MM, Mitchell RW, Halayko AJ. Epithelium-dependent modulation of responsiveness of airways from caveolin-1 knockout mice is mediated through cyclooxygenase-2 and 5-lipoxygenase. Br J Pharmacol. 2012 Oct; 167(3):548-60. PMID: 22551156.
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    50. Wright D, Sharma P, Ryu MH, Rissé PA, Ngo M, Maarsingh H, Koziol-White C, Jha A, Halayko AJ, West AR. Models to study airway smooth muscle contraction in vivo, ex vivo and in vitro: implications in understanding asthma. Pulm Pharmacol Ther. 2013 Feb; 26(1):24-36. PMID: 22967819.
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    51. Ghavami S, Yeganeh B, Stelmack GL, Kashani HH, Sharma P, Cunnington R, Rattan S, Bathe K, Klonisch T, Dixon IM, Freed DH, Halayko AJ. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. Cell Death Dis. 2012 Jun 21; 3:e330. PMID: 22717585.
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    52. Gerthoffer WT, Schaafsma D, Sharma P, Ghavami S, Halayko AJ. Motility, survival, and proliferation. Compr Physiol. 2012 Jan; 2(1):255-81. PMID: 23728975.
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    53. Halayko AJ, Sharma P. . Airway smooth muscle cells. In: Inflammation and Allergy Drug Design. Holgate ST, Izuhara K, Wills-Karp M, editors. Oxford, England: Wiley-Blackwell, John Wiley & Sons; 2011. Chapter 12; p.163-174. 344p. 2011.
    54. Ghavami S, Mutawe MM, Sharma P, Yeganeh B, McNeill KD, Klonisch T, Unruh H, Kashani HH, Schaafsma D, Los M, Halayko AJ. Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. PLoS One. 2011 Jan 31; 6(1):e16523. PMID: 21304979.
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    55. Hashemi M, Sharma P, Eshraghi M, Naderi M, Moazeni-Roodi A, Mehrabifar H, Taheri M . Alpha-1 Antitrypsin: It’s Role in Health and Disease. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 2010; 9:279-288. 2010.
    56. Sharma P, Ghavami S, Stelmack GL, McNeill KD, Mutawe MM, Klonisch T, Unruh H, Halayko AJ. beta-Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release. J Cell Sci. 2010 Sep 15; 123(Pt 18):3061-70. PMID: 20736308.
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    57. Ghavami S, Mutawe MM, Hauff K, Stelmack GL, Schaafsma D, Sharma P, McNeill KD, Hynes TS, Kung SK, Unruh H, Klonisch T, Hatch GM, Los M, Halayko AJ. Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c. Biochim Biophys Acta. 2010 Apr; 1803(4):452-67. PMID: 20045437.
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    58. Sharma P, Halayko AJ. Emerging molecular targets for the treatment of asthma. Indian J Biochem Biophys. 2009 Dec; 46(6):447-60. PMID: 20361708.
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    59. Halayko A, Sharma P . S100A8/A9 as a pro-inflammatory cytokine in obstructive airway disease via the multi-ligand receptor, RAGE. Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. 2009; 8(4):306-317. 2009.
    60. Dastidar SG, Ray A, Shirumalla R, Rajagopal D, Chaudhary S, Nanda K, Sharma P, Seth MK, Balachandran S, Gupta N, Palle V . Pharmacology of a novel, orally active PDE4 inhibitor. Pharmacology. 2009;83(5):275-86. doi: 10.1159/000209608. Epub 2009 Mar 25. PubMed PMID: 19321962. 2009.
    61. Sharma P, Halayko AJ . Emerging molecular targets for the treatment of asthma. Indian J Biochem Biophys. 2009 Dec;46(6):447-60. Review. PubMed PMID: 20361708. 2009.
    62. Hirota JA, Nguyen TT, Schaafsma D, Sharma P, Tran T. Airway smooth muscle in asthma: phenotype plasticity and function. Pulm Pharmacol Ther. 2009 Oct; 22(5):370-8. PMID: 19114115.
      Citations:    
    63. Shirumalla RK, Sharma P, Dastidar SG, Paliwal JK, Kakar S, Varshney B, Singh Saini G, Sattigeri V, Salman M, Ray A . Pharmacodynamic and pharmacokinetic characterisation of RBx 7796: a novel 5-lipoxygenase inhibitor. Inflamm Res. 2008 Mar;57(3):135-43. doi: 10.1007/s00011-007-7149-4. PubMed PMID: 18369577. 2008.
    64. Schaafsma D, McNeill KD, Stelmack GL, Gosens R, Baarsma HA, Dekkers BG, Frohwerk E, Penninks JM, Sharma P, Ens KM, Nelemans SA, Zaagsma J, Halayko AJ, Meurs H. Insulin increases the expression of contractile phenotypic markers in airway smooth muscle. Am J Physiol Cell Physiol. 2007 Jul; 293(1):C429-39. PMID: 17459944.
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