High-Temperature Requirement A Serine Peptidase 1
"High-Temperature Requirement A Serine Peptidase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted serine protease that contains a Kazal domain-like region and a C-terminal PDZ domain. It has a broad range of targets that include EXTRACELLULAR MATRIX PROTEINS; PROTEOGLYCANS; and INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS. Mutations in the HTRA1 gene are associated with AGE-RELATED MACULAR DEGENERATION 7 and Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL).
| Descriptor ID |
D000074289
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| MeSH Number(s) |
D08.811.277.656.300.760.420 D08.811.277.656.959.350.420
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "High-Temperature Requirement A Serine Peptidase 1".
Below are MeSH descriptors whose meaning is more specific than "High-Temperature Requirement A Serine Peptidase 1".
This graph shows the total number of publications written about "High-Temperature Requirement A Serine Peptidase 1" by people in this website by year, and whether "High-Temperature Requirement A Serine Peptidase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "High-Temperature Requirement A Serine Peptidase 1" by people in Profiles.
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Orlin A, Hadley D, Chang W, Ho AC, Brown G, Kaiser RS, Regillo CD, Godshalk AN, Lier A, Kaderli B, Stambolian D. Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration. Retina. 2012 Jan; 32(1):4-9.
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Hadley D, Orlin A, Brown G, Brucker AJ, Ho AC, Regillo CD, Donoso LA, Tian L, Kaderli B, Stambolian D. Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10, region q26. Invest Ophthalmol Vis Sci. 2010 Apr; 51(4):2191-6.