Tudor Domain

"Tudor Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A conserved, approximately 50 amino acid, protein sequence that adopts a characteristic strongly bent, five stranded anti-parallel beta-sheet barrel-like fold. The Tudor domain recognizes dimethylated ARGININE through its negatively-charged surface and occurs in many proteins that co-localize with RNA; RIBONUCLEOPROTEINS or SINGLE-STRANDED DNA complexes in the CELL NUCLEUS; MITOCHONDRIA; or KINETOCHORES.


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