Extracellular Vesicles

"Extracellular Vesicles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Membrane limited structures derived from cell membranes and cytoplasmic material, and released into EXTRACELLULAR SPACE. They circulate through the EXTRACELLULAR FLUID and through the peripheral blood in the MICROVASCULATURE where cells, much larger, cannot, thereby affecting a variety of intercellular communication processes.

Descriptor ID	D000067128
MeSH Number(s)	A11.284.295.588
Concept/Terms	Extracellular Vesicles Extracellular Vesicles Extracellular Vesicle Vesicle, Extracellular Vesicles, Extracellular Exovesicles Exovesicles Exovesicle Apoptotic Bodies Apoptotic Bodies Apoptotic Body Bodies, Apoptotic Body, Apoptotic

Below are MeSH descriptors whose meaning is more general than "Extracellular Vesicles".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Extracellular Space [A11.284.295]
Extracellular Vesicles [A11.284.295.588]

Below are MeSH descriptors whose meaning is related to "Extracellular Vesicles".

Below are MeSH descriptors whose meaning is more specific than "Extracellular Vesicles".

Extracellular Vesicles
Cell-Derived Microparticles
Exosomes

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Extracellular Vesicles" by people in this website by year, and whether "Extracellular Vesicles" was a major or minor topic of these publications.

Bar chart showing 65 publications over 10 distinct years, with a maximum of 12 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2015	0	1	1
2017	2	0	2
2018	7	0	7
2019	6	1	7
2020	8	1	9
2021	11	1	12
2022	10	0	10
2023	6	1	7
2024	7	2	9
2025	1	0	1

Below are the most recent publications written about "Extracellular Vesicles" by people in Profiles.

Castagnino PA, Haas DA, Musante L, Tancler NA, Tran BV, Kean R, Steck AR, Martinez LA, Mostaghel EA, Hooper DC, Kim FJ. Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles. Cancer Biol Ther. 2025 Dec; 26(1):2455722.

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Gan L, Zhao J, Yao P, Christopher TA, Lopez B, Lau WB, Koch W, Gao E, Ma X, Wang Y. Adipocyte-derived small extracellular vesicles exacerbate diabetic ischemic heart injury by promoting oxidative stress and mitochondrial-mediated cardiomyocyte apoptosis. Redox Biol. 2025 02; 79:103443.

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Jindal N, Sharma P, Punia S, Dass M, Anthwal D, Gupta RK, Bhalla M, Singhal R, Behera A, Yadav R, Sethi S, Dhooria S, Aggarwal AN, Haldar S. Utility of pleural fluid-derived extracellular vesicles as a source of Mycobacterium tuberculosis antigens MPT51 and MPT64 for pleural TB diagnosis: a proof-of-concept study. Tuberculosis (Edinb). 2025 Jan; 150:102578.

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Gomez-Galvez Y, Gupta M, Kaur M, Fusco S, Podda MV, Grassi C, Srivastava AK, Iacovitti L, Blanco-Suarez E. Recovery after human bone marrow mesenchymal stem cells (hBM-MSCs)-derived extracellular vesicles (EVs) treatment in post-MCAO rats requires repeated handling. PLoS One. 2024; 19(10):e0312298.

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Verrillo CE, Quaglia F, Shields CD, Lin S, Kossenkov AV, Tang HY, Speicher D, Naranjo NM, Testa A, Kelly WK, Liu Q, Leiby B, Musante L, Sossey-Alaoui K, Dogra N, Chen TY, Altieri DC, Languino LR. Expression of the aV?3 integrin affects prostate cancer sEV cargo and density and promotes sEV pro-tumorigenic activity in vivo through a GPI-anchored receptor, NgR2. J Extracell Vesicles. 2024 Aug; 13(8):e12482.

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Naranjo NM, Kennedy A, Testa A, Verrillo CE, Altieri AD, Kean R, Hooper DC, Yu J, Zhao J, Abinader O, Pickles MW, Hawkins A, Kelly WK, Mitra R, Languino LR. Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma. Cancer Biol Ther. 2024 Dec 31; 25(1):2364433.

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Dresselhaus EC, Harris KP, Blanchette CR, Koles K, Del Signore SJ, Pescosolido MF, Ermanoska B, Rozencwaig M, Soslowsky RC, Parisi MJ, Stewart BA, Mosca TJ, Rodal AA. ESCRT disruption provides evidence against trans-synaptic signaling via extracellular vesicles. J Cell Biol. 2024 Sep 02; 223(9).

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Kawano T, Englisch C, Hisada Y, Paul D, Archibald S, Grover S, Pabinger I, Ay C, Mackman N. Mucin 1 and venous thrombosis in tumor-bearing mice and patients with cancer. Thromb Res. 2024 05; 237:23-30.

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Kaur M, Fusco S, Van den Broek B, Aseervatham J, Rostami A, Iacovitti L, Grassi C, Lukomska B, Srivastava AK. Most recent advances and applications of extracellular vesicles in tackling neurological challenges. Med Res Rev. 2024 07; 44(4):1923-1966.

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Sorrells JE, Park J, Aksamitiene E, Marjanovic M, Martin EM, Chaney EJ, Higham AM, Cradock KA, Liu ZG, Boppart SA. Label-free nonlinear optical signatures of extracellular vesicles in liquid and tissue biopsies of human breast cancer. Sci Rep. 2024 03 06; 14(1):5528.

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