"12E7 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-LYMPHOCYTES and ROSETTE FORMATION by ERYTHROCYTES. It is also involved in the migration of LEUKOCYTES through the ENDOTHELIUM BASEMENT MEMBRANE. The 12E7 antigen co-localizes with, but functions independently of PECAM-1.
| Descriptor ID |
D000071443
|
| MeSH Number(s) |
D12.776.395.550.200.049 D12.776.543.550.200.062 D23.050.301.350.049
|
| Concept/Terms |
12E7 Antigen- 12E7 Antigen
- Antigen, 12E7
- CD99 Molecule
- 12E7 Protein
- MIC2 Protein
- Antigens, CD99
- CD99 Antigens
- T-Cell Surface Glycoprotein E2
- T Cell Surface Glycoprotein E2
- CD99 Antigen
- Antigen, CD99
- E2 Antigen
- Antigen, E2
|
Below are MeSH descriptors whose meaning is more general than "12E7 Antigen".
Below are MeSH descriptors whose meaning is more specific than "12E7 Antigen".
This graph shows the total number of publications written about "12E7 Antigen" by people in this website by year, and whether "12E7 Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "12E7 Antigen" by people in Profiles.
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Al-Daraji WI, Miettinen M. Superficial acral fibromyxoma: a clinicopathological analysis of 32 tumors including 4 in the heel. J Cutan Pathol. 2008 Nov; 35(11):1020-6.
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Scotlandi K, Zuntini M, Manara MC, Sciandra M, Rocchi A, Benini S, Nicoletti G, Bernard G, Nanni P, Lollini PL, Bernard A, Picci P. CD99 isoforms dictate opposite functions in tumour malignancy and metastases by activating or repressing c-Src kinase activity. Oncogene. 2007 Oct 11; 26(46):6604-18.
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Manara MC, Bernard G, Lollini PL, Nanni P, Zuntini M, Landuzzi L, Benini S, Lattanzi G, Sciandra M, Serra M, Colombo MP, Bernard A, Picci P, Scotlandi K. CD99 acts as an oncosuppressor in osteosarcoma. Mol Biol Cell. 2006 Apr; 17(4):1910-21.
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Scotlandi K, Perdichizzi S, Bernard G, Nicoletti G, Nanni P, Lollini PL, Curti A, Manara MC, Benini S, Bernard A, Picci P. Targeting CD99 in association with doxorubicin: an effective combined treatment for Ewing's sarcoma. Eur J Cancer. 2006 Jan; 42(1):91-6.
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Ozdemirli M, Fanburg-Smith JC, Hartmann DP, Azumi N, Miettinen M. Differentiating lymphoblastic lymphoma and Ewing's sarcoma: lymphocyte markers and gene rearrangement. Mod Pathol. 2001 Nov; 14(11):1175-82.
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Scotlandi K, Benini S, Manara MC, Serra M, Nanni P, Lollini PL, Nicoletti G, Landuzzi L, Chano T, Picci P, Baldini N. Murine model for skeletal metastases of Ewing's sarcoma. J Orthop Res. 2000 Nov; 18(6):959-66.
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Scotlandi K, Baldini N, Cerisano V, Manara MC, Benini S, Serra M, Lollini PL, Nanni P, Nicoletti G, Bernard G, Bernard A, Picci P. CD99 engagement: an effective therapeutic strategy for Ewing tumors. Cancer Res. 2000 Sep 15; 60(18):5134-42.