Below are the most recent publications written about "beta-Arrestins" by people in Profiles.
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Ippolito M, De Pascali F, Hopfinger N, Komolov KE, Laurinavichyute D, Reddy PAN, Sakkal LA, Rajkowski KZ, Nayak AP, Lee J, Lee J, Cao G, Donover PS, Reichman M, An SS, Salvino JM, Penn RB, Armen RS, Scott CP, Benovic JL. Identification of a ?-arrestin-biased negative allosteric modulator for the ?2-adrenergic receptor. Proc Natl Acad Sci U S A. 2023 08; 120(31):e2302668120.
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Shah SD, Lind C, De Pascali F, Penn RB, MacKerell AD, Deshpande DA. In silico identification of a ?2-adrenoceptor allosteric site that selectively augments canonical ?2AR-Gs signaling and function. Proc Natl Acad Sci U S A. 2022 12 06; 119(49):e2214024119.
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De Pascali F, Ippolito M, Wolfe E, Komolov KE, Hopfinger N, Lemenze D, Kim N, Armen RS, An SS, Scott CP, Benovic JL. ?2 -Adrenoceptor agonist profiling reveals biased signalling phenotypes for the ?2 -adrenoceptor with possible implications for the treatment of asthma. Br J Pharmacol. 2022 10; 179(19):4692-4708.
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Luo J, De Pascali F, Richmond GW, Khojah AM, Benovic JL. Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4. J Biol Chem. 2022 02; 298(2):101551.
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Ippolito M, De Pascali F, Inoue A, Benovic JL. Phenylalanine 193 in Extracellular Loop 2 of the ?2-Adrenergic Receptor Coordinates ?-Arrestin Interaction. Mol Pharmacol. 2022 02; 101(2):87-94.
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Pera T, Penn RB. Methods to Investigate ?-Arrestin-Mediated Regulation of GPCR Function in Human Airway Smooth Muscle. Methods Mol Biol. 2019; 1957:69-82.
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Grisanti LA, Thomas TP, Carter RL, de Lucia C, Gao E, Koch WJ, Benovic JL, Tilley DG. Pepducin-mediated cardioprotection via ?-arrestin-biased ?2-adrenergic receptor-specific signaling. Theranostics. 2018; 8(17):4664-4678.
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Luo J, Busillo JM, Stumm R, Benovic JL. G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of ?-Arrestin. Mol Pharmacol. 2017 06; 91(6):554-566.
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Carr R, Schilling J, Song J, Carter RL, Du Y, Yoo SM, Traynham CJ, Koch WJ, Cheung JY, Tilley DG, Benovic JL. ?-arrestin-biased signaling through the ?2-adrenergic receptor promotes cardiomyocyte contraction. Proc Natl Acad Sci U S A. 2016 07 12; 113(28):E4107-16.
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Rajagopal K, Saha P, Mohammed I, Sanchez PG, Li T, Wu ZJ, Griffith BP. Effects of small platform catheter-based left ventricular assist device support on regional myocardial signal transduction. J Thorac Cardiovasc Surg. 2015 Nov; 150(5):1332-41.