Cartilage Oligomeric Matrix Protein
"Cartilage Oligomeric Matrix Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Major component of chondrocyte EXTRACELLULAR MATRIX of various tissues including bone, tendon, ligament, SYNOVIUM and blood vessels. It binds MATRILIN PROTEINS and is associated with development of cartilage and bone.
| Descriptor ID |
D064236
|
| MeSH Number(s) |
D12.776.860.300.155
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| Concept/Terms |
Cartilage Oligomeric Matrix Protein- Cartilage Oligomeric Matrix Protein
- Thrombospondin 5 Protein
- Protein, Thrombospondin 5
- TSP5 (Thrombospondin-5)
- COMP (Cartilage Oligomeric Matrix Protein)
- Thrombospondin-5 Protein
- Protein, Thrombospondin-5
|
Below are MeSH descriptors whose meaning is more general than "Cartilage Oligomeric Matrix Protein".
Below are MeSH descriptors whose meaning is more specific than "Cartilage Oligomeric Matrix Protein".
This graph shows the total number of publications written about "Cartilage Oligomeric Matrix Protein" by people in this website by year, and whether "Cartilage Oligomeric Matrix Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cartilage Oligomeric Matrix Protein" by people in Profiles.
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Mazzotti A, Artioli E, Brizola E, Moroni A, Tremosini M, Di Cecco A, Gallone S, Faldini C, Sangiorgi L, Gnoli M. Multiple Osteochondritis Dissecans as Main Manifestation of Multiple Epiphyseal Dysplasia Caused by a Novel Cartilage Oligomeric Matrix Protein Pathogenic Variant: A Clinical Report. Genes (Basel). 2024 Nov 20; 15(11).
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Roman-Blas J, Dion AS, Seghatoleslami MR, Giunta K, Oca P, Jimenez SA, Williams CJ. MED and PSACH COMP mutations affect chondrogenesis in chicken limb bud micromass cultures. J Cell Physiol. 2010 Sep; 224(3):817-26.
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Kipnes JR, Xu L, Han F, Rallapalli R, Jimenez S, Hall DJ, Tuan RS, Li Y. Molecular cloning and expression patterns of mouse cartilage oligomeric matrix protein gene. Osteoarthritis Cartilage. 2000 May; 8(3):236-9.
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Dodge GR, Hawkins D, Boesler E, Sakai L, Jimenez SA. Production of cartilage oligomeric matrix protein (COMP) by cultured human dermal and synovial fibroblasts. Osteoarthritis Cartilage. 1998 Nov; 6(6):435-40.
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Christiano AM, Rosenbaum LM, Chung-Honet LC, Parente MG, Woodley DT, Pan TC, Zhang RZ, Chu ML, Burgeson RE, Uitto J. The large non-collagenous domain (NC-1) of type VII collagen is amino-terminal and chimeric. Homology to cartilage matrix protein, the type III domains of fibronectin and the A domains of von Willebrand factor. Hum Mol Genet. 1992 Oct; 1(7):475-81.