"Nucleus Pulposus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Fibrocartilage inner core of the intervertebral disc. Prolapsed or bulged nucleus pulposus leads to INTERVERTEBRAL DISC DISPLACEMENT while proliferation of cells in the nucleus pulposus is associated with INTERVERTEBRAL DISC DEGENERATION.
| Descriptor ID |
D000070614
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| MeSH Number(s) |
A02.165.308.410.500 A02.835.232.834.432.500 A10.165.382.350.050.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleus Pulposus".
Below are MeSH descriptors whose meaning is more specific than "Nucleus Pulposus".
This graph shows the total number of publications written about "Nucleus Pulposus" by people in this website by year, and whether "Nucleus Pulposus" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nucleus Pulposus" by people in Profiles.
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Sao K, Risbud MV. Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine. Matrix Biol. 2024 Aug; 131:46-61.
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Johnston SN, Madhu V, Shapiro IM, Risbud MV. Conditional Deletion of HIF-2a in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age-Dependent Structural Changes in Intervertebral Disc. J Bone Miner Res. 2022 12; 37(12):2512-2530.
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Novais EJ, Tran VA, Johnston SN, Darris KR, Roupas AJ, Sessions GA, Shapiro IM, Diekman BO, Risbud MV. Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice. Nat Commun. 2021 09 03; 12(1):5213.