"DNA End-Joining Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The repair of DOUBLE-STRAND DNA BREAKS by rejoining the broken ends of DNA to each other directly.
| Descriptor ID |
D059766
|
| MeSH Number(s) |
G02.111.222.200 G05.219.200
|
| Concept/Terms |
DNA End-Joining Repair- DNA End-Joining Repair
- DNA End Joining Repair
- End-Joining Repair, DNA
- Repair, DNA End-Joining
- End-Joining DNA Repair
- DNA Repair, End-Joining
- End Joining DNA Repair
- Repair, End-Joining DNA
Non-Homologous DNA End-Joining- Non-Homologous DNA End-Joining
- DNA End-Joining, Non-Homologous
- End-Joining, Non-Homologous DNA
- Non Homologous DNA End Joining
- Nonhomologous DNA End-Joining
- DNA End-Joining, Nonhomologous
- Nonhomologous DNA End Joining
- NHEJ DNA Repair
- DNA Repair, NHEJ
- Repair, NHEJ DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA End-Joining Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA End-Joining Repair".
This graph shows the total number of publications written about "DNA End-Joining Repair" by people in this website by year, and whether "DNA End-Joining Repair" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 3 | 2 | 5 |
| 2013 | 6 | 1 | 7 |
| 2014 | 2 | 0 | 2 |
| 2015 | 4 | 0 | 4 |
| 2016 | 3 | 0 | 3 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 1 | 4 |
| 2020 | 3 | 2 | 5 |
| 2021 | 5 | 1 | 6 |
| 2022 | 2 | 4 | 6 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "DNA End-Joining Repair" by people in Profiles.
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Lin X, Soni A, Hessenow R, Sun Y, Mladenov E, Guberina M, Stuschke M, Iliakis G. Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Pol? inhibition. Radiother Oncol. 2024 11; 200:110475.
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Vekariya U, Minakhin L, Chandramouly G, Tyagi M, Kent T, Sullivan-Reed K, Atkins J, Ralph D, Nieborowska-Skorska M, Kukuyan AM, Tang HY, Pomerantz RT, Skorski T. PARG is essential for Pol?-mediated DNA end-joining by removing repressive poly-ADP-ribose marks. Nat Commun. 2024 07 11; 15(1):5822.
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Leal AF, Herreno-Pach?n AM, Benincore-Fl?rez E, Karunathilaka A, Tomatsu S. Current Strategies for Increasing Knock-In Efficiency in CRISPR/Cas9-Based Approaches. Int J Mol Sci. 2024 Feb 20; 25(5).
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Mladenov E, Mladenova V, Stuschke M, Iliakis G. New Facets of DNA Double Strand Break Repair: Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement. Int J Mol Sci. 2023 Oct 06; 24(19).
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Haberland VMM, Magin S, Iliakis G, Hartwig A. Impact of Manganese and Chromate on Specific DNA Double-Strand Break Repair Pathways. Int J Mol Sci. 2023 Jun 20; 24(12).
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Chandramouly G, Jamsen J, Borisonnik N, Tyagi M, Calbert ML, Tredinnick T, Ozdemir AY, Kent T, Demidova EV, Arora S, Wilson SH, Pomerantz RT. Pol? promotes microhomology-mediated end-joining. Nat Struct Mol Biol. 2023 01; 30(1):107-114.
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Pei X, Mladenov E, Soni A, Li F, Stuschke M, Iliakis G. PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination. Int J Mol Sci. 2022 Oct 25; 23(21).
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Mladenov E, Paul-Konietzko K, Mladenova V, Stuschke M, Iliakis G. Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination. Int J Mol Sci. 2022 Aug 16; 23(16).
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Hanscom T, Woodward N, Batorsky R, Brown AJ, Roberts SA, McVey M. Characterization of sequence contexts that favor alternative end joining at Cas9-induced double-strand breaks. Nucleic Acids Res. 2022 07 22; 50(13):7465-7478.
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Xiao H, Li F, Mladenov E, Soni A, Mladenova V, Pan B, Dueva R, Stuschke M, Timmermann B, Iliakis G. Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ. Cells. 2022 07 02; 11(13).