PAX6 Transcription Factor
"PAX6 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A paired box transcription factor that has important functions in the development of the eye, nose, central nervous system and pancreas. Mutations in the PAX6 gene are associated with ocular disorders such as ANIRIDIA.
| Descriptor ID |
D000071841
|
| MeSH Number(s) |
D12.776.260.645.813 D12.776.930.700.813
|
| Concept/Terms |
PAX6 Transcription Factor- PAX6 Transcription Factor
- Factor, PAX6 Transcription
- Transcription Factor, PAX6
- Pax-6 Protein
- Pax 6 Protein
- Protein, Pax-6
- Paired Box Gene 6 Protein
- Oculorhombin
- Paired Box Transcription Factor 6
- Transcription Factor PAX6
- Factor PAX6, Transcription
- PAX6, Transcription Factor
- Aniridia Type II Protein
- PAX6 Protein
- Protein, PAX6
- Paired Box Protein Pax-6
- Paired Box Protein Pax 6
|
Below are MeSH descriptors whose meaning is more general than "PAX6 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "PAX6 Transcription Factor".
This graph shows the total number of publications written about "PAX6 Transcription Factor" by people in this website by year, and whether "PAX6 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "PAX6 Transcription Factor" by people in Profiles.
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Hu B, Wang Q, Wang YA, Hua S, Sauv? CG, Ong D, Lan ZD, Chang Q, Ho YW, Monasterio MM, Lu X, Zhong Y, Zhang J, Deng P, Tan Z, Wang G, Liao WT, Corley LJ, Yan H, Zhang J, You Y, Liu N, Cai L, Finocchiaro G, Phillips JJ, Berger MS, Spring DJ, Hu J, Sulman EP, Fuller GN, Chin L, Verhaak RGW, DePinho RA. Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 2016 11 17; 167(5):1281-1295.e18.
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Bardakjian TM, Schneider A. The genetics of anophthalmia and microphthalmia. Curr Opin Ophthalmol. 2011 Sep; 22(5):309-13.
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Sisodiya SM, Ragge NK, Cavalleri GL, Hever A, Lorenz B, Schneider A, Williamson KA, Stevens JM, Free SL, Thompson PJ, van Heyningen V, Fitzpatrick DR. Role of SOX2 mutations in human hippocampal malformations and epilepsy. Epilepsia. 2006 Mar; 47(3):534-42.
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Mazet F, Hutt JA, Millard J, Shimeld SM. Pax gene expression in the developing central nervous system of Ciona intestinalis. Gene Expr Patterns. 2003 Dec; 3(6):743-5.
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Reeves FC, Burdge GC, Fredericks WJ, Rauscher FJ, Lillycrop KA. Induction of antisense Pax-3 expression leads to the rapid morphological differentiation of neuronal cells and an altered response to the mitogenic growth factor bFGF. J Cell Sci. 1999 Jan; 112 ( Pt 2):253-61.