Triggering Receptor Expressed on Myeloid Cells-1
"Triggering Receptor Expressed on Myeloid Cells-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
Descriptor ID |
D000073871
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MeSH Number(s) |
D12.776.395.550.919 D12.776.543.550.919 D12.776.543.750.705.985
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Concept/Terms |
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This graph shows the total number of publications written about "Triggering Receptor Expressed on Myeloid Cells-1" by people in this website by year, and whether "Triggering Receptor Expressed on Myeloid Cells-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Triggering Receptor Expressed on Myeloid Cells-1" by people in Profiles.
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Kelker MS, Debler EW, Wilson IA. Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A. J Mol Biol. 2004 Dec 10; 344(5):1175-81.