Triggering Receptor Expressed on Myeloid Cells-1
"Triggering Receptor Expressed on Myeloid Cells-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
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