Calcium Channels

"Calcium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.

Descriptor ID	D015220
MeSH Number(s)	D12.776.157.530.400.150 D12.776.543.550.450.150 D12.776.543.585.400.150
Concept/Terms	Calcium Channels Calcium Channels Ion Channel, Calcium Calcium Ion Channel Ion Channels, Calcium Calcium Ion Channels Calcium Channel Blocker Receptor VDCC Receptors, Calcium Channel Blocker Calcium Channel Antagonist Receptors Receptors, Calcium Channel Antagonist Calcium Channel Antagonist Receptor Voltage-Dependent Calcium Channels Calcium Channels, Voltage-Dependent Channels, Voltage-Dependent Calcium Voltage Dependent Calcium Channels Calcium Channel Calcium Channel Blocker Receptors

Below are MeSH descriptors whose meaning is more general than "Calcium Channels".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Channels [D12.776.157.530.400]
Calcium Channels [D12.776.157.530.400.150]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Ion Channels [D12.776.543.550.450]
Calcium Channels [D12.776.543.550.450.150]
Membrane Transport Proteins [D12.776.543.585]
Ion Channels [D12.776.543.585.400]
Calcium Channels [D12.776.543.585.400.150]

Below are MeSH descriptors whose meaning is related to "Calcium Channels".

Below are MeSH descriptors whose meaning is more specific than "Calcium Channels".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Calcium Channels" by people in this website by year, and whether "Calcium Channels" was a major or minor topic of these publications.

Bar chart showing 41 publications over 18 distinct years, with a maximum of 8 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	2	0	2
2003	2	2	4
2004	3	0	3
2005	7	1	8
2006	2	0	2
2007	1	0	1
2008	1	0	1
2009	1	0	1
2010	4	1	5
2011	1	4	5
2012	0	1	1
2015	1	0	1
2016	1	0	1
2017	0	1	1
2021	0	1	1
2022	1	0	1
2023	1	1	2
2024	0	1	1

Below are the most recent publications written about "Calcium Channels" by people in Profiles.

Hasan P, Berezhnaya E, Rodr?guez-Prados M, Weaver D, Bekeova C, Cartes-Saavedra B, Birch E, Beyer AM, Santos JH, Seifert EL, Elrod JW, Hajn?czky G. MICU1 and MICU2 control mitochondrial calcium signaling in the mammalian heart. Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35):e2402491121.

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Rodr?guez-Prados M, Huang KT, M?rta K, Paillard M, Csord?s G, Joseph SK, Hajn?czky G. MICU1 controls the sensitivity of the mitochondrial Ca2+ uniporter to activators and inhibitors. Cell Chem Biol. 2023 Jun 15; 30(6):606-617.e4.

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Tomar D, Thomas M, Garbincius JF, Kolmetzky DW, Salik O, Jadiya P, Joseph SK, Carpenter AC, Hajn?czky G, Elrod JW. MICU1 regulates mitochondrial cristae structure and function independently of the mitochondrial Ca2+ uniporter channel. Sci Signal. 2023 04 25; 16(782):eabi8948.

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Carlson EJ, Francis R, Liu Y, Li P, Lyon M, Santi CM, Hook DJ, Hawkinson JE, Georg GI. Discovery and Characterization of Multiple Classes of Human CatSper Blockers. ChemMedChem. 2022 08 03; 17(15):e202000499.

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Booth DM, Várnai P, Joseph SK, Hajnóczky G. Oxidative bursts of single mitochondria mediate retrograde signaling toward the ER. Mol Cell. 2021 09 16; 81(18):3866-3876.e2.

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Moon SH, Liu X, Cedars AM, Yang K, Kiebish MA, Joseph SM, Kelley J, Jenkins CM, Gross RW. Heart failure-induced activation of phospholipase iPLA2? generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore. J Biol Chem. 2018 01 05; 293(1):115-129.

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Gardinier KM, Gernert DL, Porter WJ, Reel JK, Ornstein PL, Spinazze P, Stevens FC, Hahn P, Hollinshead SP, Mayhugh D, Schkeryantz J, Khilevich A, De Frutos O, Gleason SD, Kato AS, Luffer-Atlas D, Desai PV, Swanson S, Burris KD, Ding C, Heinz BA, Need AB, Barth VN, Stephenson GA, Diseroad BA, Woods TA, Yu H, Bredt D, Witkin JM. Discovery of the First a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) ?-8. J Med Chem. 2016 05 26; 59(10):4753-68.

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Jha A, Sharma P, Anaparti V, Ryu MH, Halayko AJ. A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness? Can J Physiol Pharmacol. 2015 Mar; 93(3):171-6.

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Aravindan RG, Fomin VP, Naik UP, Modelski MJ, Naik MU, Galileo DS, Duncan RL, Martin-Deleon PA. CASK interacts with PMCA4b and JAM-A on the mouse sperm flagellum to regulate Ca2+ homeostasis and motility. J Cell Physiol. 2012 Aug; 227(8):3138-50.

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Thompson WR, Majid AS, Czymmek KJ, Ruff AL, García J, Duncan RL, Farach-Carson MC. Association of the a(2)d(1) subunit with Ca(v)3.2 enhances membrane expression and regulates mechanically induced ATP release in MLO-Y4 osteocytes. J Bone Miner Res. 2011 Sep; 26(9):2125-39.

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