"Osteonectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.
| Descriptor ID |
D015676
|
| MeSH Number(s) |
D12.776.157.125.715 D12.776.395.600
|
| Concept/Terms |
Osteonectin- Osteonectin
- SPARC Glycoprotein
- BM-40
- Basement Membrane Tumor Protein
- BM 40 Protein
|
Below are MeSH descriptors whose meaning is more general than "Osteonectin".
Below are MeSH descriptors whose meaning is more specific than "Osteonectin".
This graph shows the total number of publications written about "Osteonectin" by people in this website by year, and whether "Osteonectin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Osteonectin" by people in Profiles.
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Witkiewicz AK, Freydin B, Chervoneva I, Potoczek M, Rizzo W, Rui H, Brody JR, Schwartz GF, Lisanti MP. Stromal CD10 and SPARC expression in ductal carcinoma in situ (DCIS) patients predicts disease recurrence. Cancer Biol Ther. 2010 Aug; 10(4):391-6.
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Infante JR, Matsubayashi H, Sato N, Tonascia J, Klein AP, Riall TA, Yeo C, Iacobuzio-Donahue C, Goggins M. Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma. J Clin Oncol. 2007 Jan 20; 25(3):319-25.
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Wang H, Fertala A, Ratner BD, Sage EH, Jiang S. Identifying the SPARC binding sites on collagen I and procollagen I by atomic force microscopy. Anal Chem. 2005 Nov 1; 77(21):6765-71.
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Sullivan MM, Sage EH. Hevin/SC1, a matricellular glycoprotein and potential tumor-suppressor of the SPARC/BM-40/Osteonectin family. Int J Biochem Cell Biol. 2004 Jun; 36(6):991-6.
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Basu A, Rodeck U, Prendergast GC, Howe CC. Loss of insulin-like growth factor I receptor-dependent expression of p107 and cyclin A in cells that lack the extracellular matrix protein secreted protein acidic and rich in cysteine. Cell Growth Differ. 1999 Nov; 10(11):721-8.