Osteonectin

"Osteonectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.

Descriptor ID	D015676
MeSH Number(s)	D12.776.157.125.715 D12.776.395.600
Concept/Terms	Osteonectin Osteonectin SPARC Glycoprotein BM-40 Basement Membrane Tumor Protein BM 40 Protein

Below are MeSH descriptors whose meaning is more general than "Osteonectin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Calcium-Binding Proteins [D12.776.157.125]
Osteonectin [D12.776.157.125.715]
Glycoproteins [D12.776.395]
Osteonectin [D12.776.395.600]

Below are MeSH descriptors whose meaning is related to "Osteonectin".

Below are MeSH descriptors whose meaning is more specific than "Osteonectin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Osteonectin" by people in this website by year, and whether "Osteonectin" was a major or minor topic of these publications.

Bar chart showing 8 publications over 8 distinct years, with a maximum of 1 publications in 1999 and 2004 and 2005 and 2007 and 2009 and 2010 and 2011 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2004	0	1	1
2005	1	0	1
2007	1	0	1
2009	1	0	1
2010	1	0	1
2011	1	0	1
2014	1	0	1

Below are the most recent publications written about "Osteonectin" by people in Profiles.

MacDonald WW, Swaminathan SS, Heo JY, Castillejos A, Hsueh J, Liu BJ, Jo D, Du A, Lee H, Kang MH, Rhee DJ. Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2022 06 01; 63(6):8.

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Tsiogka A, Karmiris E, Samoli E, Spaeth GL. Comparison of Central and Peripheral Contrast Sensitivity Between Healthy and Refractive Surgery Patients Using the Spaeth/Richman Contrast Sensitivity (SPARCS) Test. J Refract Surg. 2022 Feb; 38(2):128-133.

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Yu L, Zheng Y, Liu BJ, Kang MH, Millar JC, Rhee DJ. Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facility. PLoS One. 2020; 15(11):e0241294.

View in: PubMed
Scavelli K, Chatterjee A, Rhee DJ. Secreted Protein Acidic and Rich in Cysteine in Ocular Tissue. J Ocul Pharmacol Ther. 2015 Sep; 31(7):396-405.

View in: PubMed
Houghton PJ, Kurmasheva RT, Kolb EA, Gorlick R, Maris JM, Wu J, Tong Z, Arnold MA, Chatterjee M, Williams TM, Smith MA. Initial testing (stage 1) of the tubulin binding agent nanoparticle albumin-bound (nab) paclitaxel (Abraxane(?)) by the Pediatric Preclinical Testing Program (PPTP). Pediatr Blood Cancer. 2015 Jul; 62(7):1214-21.

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Swaminathan SS, Oh DJ, Kang MH, Shepard AR, Pang IH, Rhee DJ. TGF-?2-mediated ocular hypertension is attenuated in SPARC-null mice. Invest Ophthalmol Vis Sci. 2014 Jun 06; 55(7):4084-97.

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Villarreal G, Chatterjee A, Oh SS, Oh DJ, Rhee DJ. Pharmacological regulation of SPARC by lovastatin in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2014 Mar 19; 55(3):1657-65.

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Keller KE, Vranka JA, Haddadin RI, Kang MH, Oh DJ, Rhee DJ, Yang YF, Sun YY, Kelley MJ, Acott TS. The effects of tenascin C knockdown on trabecular meshwork outflow resistance. Invest Ophthalmol Vis Sci. 2013 Aug 19; 54(8):5613-23.

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Chatterjee A, Oh DJ, Kang MH, Rhee DJ. Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins. Exp Eye Res. 2013 Oct; 115:106-12.

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Oh DJ, Kang MH, Ooi YH, Choi KR, Sage EH, Rhee DJ. Overexpression of SPARC in human trabecular meshwork increases intraocular pressure and alters extracellular matrix. Invest Ophthalmol Vis Sci. 2013 May 07; 54(5):3309-19.

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