"Giant Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
| Descriptor ID |
D015726
|
| MeSH Number(s) |
A11.500
|
| Concept/Terms |
Giant Cells- Giant Cells
- Cell, Giant
- Cells, Giant
- Giant Cell
- Syncytium
- Polykaryocytes
- Polykaryocyte
- Syncytia
- Giant Cells, Multinucleated
- Cell, Multinucleated Giant
- Cells, Multinucleated Giant
- Giant Cell, Multinucleated
- Multinucleated Giant Cell
- Multinucleated Giant Cells
|
Below are MeSH descriptors whose meaning is more general than "Giant Cells".
Below are MeSH descriptors whose meaning is more specific than "Giant Cells".
This graph shows the total number of publications written about "Giant Cells" by people in this website by year, and whether "Giant Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Giant Cells" by people in Profiles.
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Gonzalez Moret YA, Jarrett SA, Ahktar H, Moghbeli N, Hasni S, Bozorgnia B, Bhat RR. Unraveling the Uncommon: A Case Report of Giant Cell Myocarditis and Examination of Existing Literature. Am J Case Rep. 2024 Mar 03; 25:e942381.
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Herlitz LC, Zdunek MP, D'Agati VD, Markowitz GS. The big squeeze: giant cells in granulomatous interstitial nephritis. Kidney Int. 2011 Aug; 80(4):434.
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Naik MU, Naik UP. Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression. Int J Biochem Cell Biol. 2011 Jan; 43(1):120-9.
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Baxter RM, Ianuzzi A, Freeman TA, Kurtz SM, Steinbeck MJ. Distinct immunohistomorphologic changes in periprosthetic hip tissues from historical and highly crosslinked UHMWPE implant retrievals. J Biomed Mater Res A. 2010 Oct; 95(1):68-78.
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Pribitkin EA, Ambro BT, Bloeden E, O'Hara BJ. Rabbit ear cartilage regeneration with a small intestinal submucosa graft. Laryngoscope. 2004 Sep; 114(9 Pt 2 Suppl 102):1-19.