Antigen-Presenting Cells

"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.

Descriptor ID	D000938
MeSH Number(s)	A11.066 A15.382.066
Concept/Terms	Antigen-Presenting Cells Antigen-Presenting Cells Antigen Presenting Cells Antigen-Presenting Cell Cell, Antigen-Presenting Cells, Antigen-Presenting Accessory Cells, Immunologic Immunologic Accessory Cells Cells, Immunologic Accessory Immunologic Accessory Cell Accessory Cell, Immunologic Cell, Immunologic Accessory

Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".

Anatomy [A]
Cells [A11]
Antigen-Presenting Cells [A11.066]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Antigen-Presenting Cells [A15.382.066]

Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.

Bar chart showing 21 publications over 14 distinct years, with a maximum of 3 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2005	1	0	1
2006	1	0	1
2007	1	0	1
2009	1	1	2
2010	0	2	2
2011	0	1	1
2013	1	1	2
2014	1	2	3
2015	0	2	2
2016	0	1	1
2017	0	1	1
2021	1	1	2

Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.

Knudson CJ, F?rez M, Alves-Peixoto P, Erkes DA, Melo-Silva CR, Tang L, Snyder CM, Sigal LJ. Mechanisms of Antiviral Cytotoxic CD4 T Cell Differentiation. J Virol. 2021 09 09; 95(19):e0056621.

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Toulmin SA, Bhadiadra C, Paris AJ, Lin JH, Katzen J, Basil MC, Morrisey EE, Worthen GS, Eisenlohr LC. Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation. Nat Commun. 2021 06 28; 12(1):3993.

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Rezk AF, Kemp DM, El-Domyati M, El-Din WH, Lee JB, Uitto J, Igoucheva O, Alexeev V. Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and?Progression. J Invest Dermatol. 2017 05; 137(5):1126-1134.

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Leitch CS, Natafji E, Yu C, Abdul-Ghaffar S, Madarasingha N, Venables ZC, Chu R, Fitch PM, Muinonen-Martin AJ, Campbell LE, McLean WH, Schwarze J, Howie SE, Weller RB. Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells. J Allergy Clin Immunol. 2016 08; 138(2):482-490.e7.

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Small EJ, Lance RS, Gardner TA, Karsh LI, Fong L, McCoy C, DeVries T, Sheikh NA, GuhaThakurta D, Chang N, Redfern CH, Shore ND. A Randomized Phase II Trial of Sipuleucel-T with Concurrent versus Sequential Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer. Clin Cancer Res. 2015 Sep 01; 21(17):3862-9.

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Sawyer DM, Amenta PS, Medel R, Dumont AS. Inflammatory mediators in vascular disease: identifying promising targets for intracranial aneurysm research. Mediators Inflamm. 2015; 2015:896283.

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Ngo MC, Ando J, Leen AM, Ennamuri S, Lapteva N, Vera JF, Min-Venditti A, Mims MP, Heslop HE, Bollard CM, Gottschalk S, Rooney CM. Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity. J Immunother. 2014 May; 37(4):193-203.

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Walline CC, Deffit SN, Wang N, Guindon LM, Crotzer VL, Liu J, Hollister K, Eisenlohr LC, Brutkiewicz RR, Kaplan MH, Blum JS. Virus-encoded ectopic CD74 enhances poxvirus vaccine efficacy. Immunology. 2014 Apr; 141(4):531-9.

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Curry JM, Sprandio J, Cognetti D, Luginbuhl A, Bar-ad V, Pribitkin E, Tuluc M. Tumor microenvironment in head and neck squamous cell carcinoma. Semin Oncol. 2014 Apr; 41(2):217-34.

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Farrington LA, Smith TA, Grey F, Hill AB, Snyder CM. Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection. J Immunol. 2013 Apr 01; 190(7):3410-6.

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