"Eicosanoids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of compounds named after and generally derived from C20 fatty acids (EICOSANOIC ACIDS) that includes PROSTAGLANDINS; LEUKOTRIENES; THROMBOXANES, and HYDROXYEICOSATETRAENOIC ACIDS. They have hormone-like effects mediated by specialized receptors (RECEPTORS, EICOSANOID).
| Descriptor ID |
D015777
|
| MeSH Number(s) |
D10.251.355.255 D23.469.050.175
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Eicosanoids".
Below are MeSH descriptors whose meaning is more specific than "Eicosanoids".
This graph shows the total number of publications written about "Eicosanoids" by people in this website by year, and whether "Eicosanoids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Eicosanoids" by people in Profiles.
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Yamaguchi A, van Hoorebeke C, Tourdot BE, Perry SC, Lee G, Rhoads N, Rickenberg A, Green AR, Sorrentino J, Yeung J, Freedman JC, Holman TR, Holinstat M. Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids. Pharmacol Res Perspect. 2023 Feb; 11(1):e01056.
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Kim S, Lee ES, Lee EJ, Jung JY, Lee SB, Lee HJ, Kim J, Kim HJ, Lee JW, Son BH, Gong G, Ahn SH, Chang S. Targeted eicosanoids profiling reveals a prostaglandin reprogramming in breast Cancer by microRNA-155. J Exp Clin Cancer Res. 2021 Jan 25; 40(1):43.
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Liu X, Zhang S, Arora JS, Snyder NW, Shah SJ, Blair IA. 11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid. Chem Res Toxicol. 2011 Dec 19; 24(12):2227-36.
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Holinstat M, Boutaud O, Apopa PL, Vesci J, Bala M, Oates JA, Hamm HE. Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2a differently for cyclooxygenase-1 and 12-lipoxygenase catalysis. Arterioscler Thromb Vasc Biol. 2011 Feb; 31(2):435-42.
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Edelman MJ, Watson D, Wang X, Morrison C, Kratzke RA, Jewell S, Hodgson L, Mauer AM, Gajra A, Masters GA, Bedor M, Vokes EE, Green MJ. Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy--Cancer and Leukemia Group B Trial 30203. J Clin Oncol. 2008 Feb 20; 26(6):848-55.
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Pasqualini ME, Berra MA, Calder?n RO, Cremonezzi DC, Giraudo C, Eynard AR. Dietary lipids modulate eicosanoid release and apoptosis of cells of a murine lung alveolar carcinoma. Prostaglandins Leukot Essent Fatty Acids. 2005 Apr; 72(4):235-40.
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Patrono C, Ciabattoni G, Patrignani P, Rocca B, Landolfi R. Eicosanoid biosynthesis and metabolism in myeloproliferative disorders. Ann N Y Acad Sci. 1994 Nov 15; 744:229-36.
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Pi F, Hotter G, Closa D, Rosell?-Catafau J, Bulbena O, Badosa F, Morris M, Fern?ndez-Cruz L, Gelpi E. Effect of a platelet-activating factor antagonist and desferrioxamine administration on eicosanoid production in rat pancreas transplantation. Transplantation. 1994 Jan; 57(1):12-7.
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Cipolle MD, Pasquale MD, Cerra FB. Secondary organ dysfunction. From clinical perspectives to molecular mediators. Crit Care Clin. 1993 Apr; 9(2):261-98.