Cadherins

"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.

Descriptor ID	D015820
MeSH Number(s)	D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
Concept/Terms	Cadherins Cadherins Liver Cell Adhesion Molecule Liver Cell Adhesion Molecule Liver Cell Adhesion Molecules P-Cadherins P-Cadherins P Cadherins P-Cadherin P Cadherin Placental Cadherins Cadherins, Placental Cadherin-3 Cadherin 3 E-Cadherins E-Cadherins E Cadherins Uvomorulin Epithelial-Cadherins Epithelial Cadherins Cadherin-1 Cadherin 1 E-Cadherin E Cadherin N-Cadherins N-Cadherins N Cadherins N-Cadherin N Cadherin Neural Cadherins Cadherins, Neural Cadherin-2 Cadherin 2

Below are MeSH descriptors whose meaning is more general than "Cadherins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Cell Adhesion Molecules [D12.776.395.550.200]
Cadherins [D12.776.395.550.200.200]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Cell Adhesion Molecules [D12.776.543.550.200]
Cadherins [D12.776.543.550.200.200]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Cell Adhesion Molecules [D23.050.301.350]
Cadherins [D23.050.301.350.200]

Below are MeSH descriptors whose meaning is more specific than "Cadherins".

Cadherins
Desmosomal Cadherins

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.

Bar chart showing 94 publications over 29 distinct years, with a maximum of 9 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	4	0	4
1998	1	0	1
1999	4	0	4
2000	5	1	6
2001	6	1	7
2002	3	2	5
2003	2	2	4
2004	2	0	2
2005	1	1	2
2006	1	3	4
2007	0	2	2
2008	2	0	2
2009	1	3	4
2010	2	7	9
2011	4	3	7
2012	0	1	1
2013	2	3	5
2014	0	1	1
2015	1	1	2
2016	1	2	3
2017	4	2	6
2018	0	1	1
2019	2	1	3
2020	2	2	4
2022	0	1	1
2023	0	1	1
2024	0	1	1
2025	1	0	1

Below are the most recent publications written about "Cadherins" by people in Profiles.

Moazzeni S, Kyker-Snowman K, Cohen RI, Wang H, Li R, Shreiber DI, Zahn JD, Shi Z, Lin H. N-Cadherin based adhesion and Rac1 activity regulate tension polarization in the actin cortex. Sci Rep. 2025 02 04; 15(1):4296.

View in: PubMed
Gallanis AF, Bowden C, Lopez R, Gamble LA, Samaranayake SG, Payne C, Snyder D, Fasaye GA, Joyce S, Broesamle R, Miao N, Miettinen M, Quezado M, Kim SA, Korman L, Heller T, Blakely AM, Hernandez JM, Davis JL. Lessons learned from 150 total gastrectomies for prevention of cancer. J Gastrointest Surg. 2025 01; 29(1):101889.

View in: PubMed
Green BL, Gamble LA, Diggs LP, Nousome D, Patterson JC, Joughin BA, Gasmi B, Lux SC, Samaranayake SG, Miettinen M, Quezado M, Hernandez JM, Yaffe MB, Davis JL. Early Immune Changes Support Signet Ring Cell Dormancy in CDH1-Driven Hereditary Diffuse Gastric Carcinogenesis. Mol Cancer Res. 2023 12 01; 21(12):1356-1365.

View in: PubMed
Baqai U, Purwin TJ, Bechtel N, Chua V, Han A, Hartsough EJ, Kuznetsoff JN, Harbour JW, Aplin AE. Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma. Mol Cancer Res. 2022 08 05; 20(8):1260-1271.

View in: PubMed
Curtin BF, Gamble LA, Schueler SA, Ruff SM, Quezado M, Miettinen M, Fasaye GA, Passi M, Hernandez JM, Heller T, Koh C, Davis JL. Enhanced endoscopic detection of occult gastric cancer in carriers of pathogenic CDH1 variants. J Gastroenterol. 2021 02; 56(2):139-146.

View in: PubMed
Mao L, Yang J, Yue J, Chen Y, Zhou H, Fan D, Zhang Q, Buraschi S, Iozzo RV, Bi X. Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis. Matrix Biol. 2021 01; 95:1-14.

View in: PubMed
Shahbazi MN, Wang T, Tao X, Weatherbee BAT, Sun L, Zhan Y, Keller L, Smith GD, Pellicer A, Scott RT, Seli E, Zernicka-Goetz M. Developmental potential of aneuploid human embryos cultured beyond implantation. Nat Commun. 2020 08 10; 11(1):3987.

View in: PubMed
Lee JYW, McGrath JA. Mutations in genes encoding desmosomal proteins: spectrum of cutaneous and extracutaneous abnormalities. Br J Dermatol. 2021 04; 184(4):596-605.

View in: PubMed
Pellicani R, Poletto E, Andreuzzi E, Paulitti A, Doliana R, Bizzotto D, Braghetta P, Colladel R, Tarticchio G, Sabatelli P, Bucciotti F, Bressan G, Iozzo RV, Colombatti A, Bonaldo P, Mongiat M. Multimerin-2 maintains vascular stability and permeability. Matrix Biol. 2020 05; 87:11-25.

View in: PubMed
Gandhi JK, Knudsen T, Hill M, Roy B, Bachman L, Pfannkoch-Andrews C, Schmidt KN, Metko MM, Ackerman MJ, Resch Z, Pulido JS, Marmorstein AD. Human Fibrinogen for Maintenance and Differentiation of Induced Pluripotent Stem Cells in Two Dimensions and Three Dimensions. Stem Cells Transl Med. 2019 06; 8(6):512-521.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement