Eukaryotic Initiation Factor-2
"Eukaryotic Initiation Factor-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eukaryotic initiation factor of protein synthesis. In higher eukaryotes the factor consists of three subunits: alpha, beta, and gamma. As initiation proceeds, eIF-2 forms a ternary complex with Met-tRNAi and GTP.
| Descriptor ID |
D015852
|
| MeSH Number(s) |
D12.776.835.725.868.249
|
| Concept/Terms |
Eukaryotic Initiation Factor-2- Eukaryotic Initiation Factor-2
- Eukaryotic Initiation Factor 2
- Initiation Factor-2, Eukaryotic
- Peptide Initiation Factor EIF-2
- Peptide Initiation Factor EIF 2
- Eukaryotic Peptide Initiation Factor-2
- Eukaryotic Peptide Initiation Factor 2
- EIF-2
- EIF 2
- EIF2
|
Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-2".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-2".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-2" by people in this website by year, and whether "Eukaryotic Initiation Factor-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-2" by people in Profiles.
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Tan GS, Garchow BG, Liu X, Metzler D, Kiriakidou M. Clarifying mammalian RISC assembly in vitro. BMC Mol Biol. 2011; 12:19.
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Tan GS, Garchow BG, Liu X, Yeung J, Morris JP, Cuellar TL, McManus MT, Kiriakidou M. Expanded RNA-binding activities of mammalian Argonaute 2. Nucleic Acids Res. 2009 Dec; 37(22):7533-45.
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Nelson PT, De Planell-Saguer M, Lamprinaki S, Kiriakidou M, Zhang P, O'Doherty U, Mourelatos Z. A novel monoclonal antibody against human Argonaute proteins reveals unexpected characteristics of miRNAs in human blood cells. RNA. 2007 Oct; 13(10):1787-92.
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Kiriakidou M, Tan GS, Lamprinaki S, De Planell-Saguer M, Nelson PT, Mourelatos Z. An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell. 2007 Jun 15; 129(6):1141-51.