Purpura, Thrombocytopenic, Idiopathic
"Purpura, Thrombocytopenic, Idiopathic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
| Descriptor ID |
D016553
|
| MeSH Number(s) |
C15.378.100.802.687.600 C15.378.140.855.925.750.600 C15.378.463.740 C20.111.759 C20.841.600 C23.550.414.950.687.600 C23.888.885.687.687.600
|
| Concept/Terms |
Purpura, Thrombocytopenic, Idiopathic- Purpura, Thrombocytopenic, Idiopathic
- Idiopathic Thrombocytopenic Purpura
- Idiopathic Thrombocytopenic Purpuras
- Purpura, Idiopathic Thrombocytopenic
- Purpuras, Idiopathic Thrombocytopenic
- Thrombocytopenic Purpura, Idiopathic
- Thrombocytopenic Purpuras, Idiopathic
- Immune Thrombocytopenic Purpura
- Immune Thrombocytopenic Purpuras
- Purpura, Immune Thrombocytopenic
- Purpuras, Immune Thrombocytopenic
- Thrombocytopenic Purpura, Immune
- Thrombocytopenic Purpuras, Immune
- Immune Thrombocytopenia
- Immune Thrombocytopenias
- Thrombocytopenia, Immune
- Thrombocytopenias, Immune
- Thrombocytopenic Purpura, Autoimmune
- Werlhof Disease
- Disease, Werlhof
- Werlhof's Disease
- Disease, Werlhof's
- Werlhofs Disease
- Autoimmune Thrombocytopenia
- Autoimmune Thrombocytopenias
- Thrombocytopenia, Autoimmune
- Thrombocytopenias, Autoimmune
- Autoimmune Thrombocytopenic Purpura
- Autoimmune Thrombocytopenic Purpuras
- Purpura, Autoimmune Thrombocytopenic
- Purpuras, Autoimmune Thrombocytopenic
- Purpura, Thrombocytopenic, Autoimmune
|
Below are MeSH descriptors whose meaning is more general than "Purpura, Thrombocytopenic, Idiopathic".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Blood Coagulation Disorders [C15.378.100]
- Purpura [C15.378.100.802]
- Purpura, Thrombocytopenic [C15.378.100.802.687]
- Purpura, Thrombocytopenic, Idiopathic [C15.378.100.802.687.600]
- Blood Platelet Disorders [C15.378.140]
- Thrombocytopenia [C15.378.140.855]
- Thrombotic Microangiopathies [C15.378.140.855.925]
- Purpura, Thrombocytopenic [C15.378.140.855.925.750]
- Purpura, Thrombocytopenic, Idiopathic [C15.378.140.855.925.750.600]
- Hemorrhagic Disorders [C15.378.463]
- Purpura, Thrombocytopenic, Idiopathic [C15.378.463.740]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Purpura, Thrombocytopenic, Idiopathic [C20.111.759]
- Purpura, Thrombocytopenic [C20.841]
- Purpura, Thrombocytopenic, Idiopathic [C20.841.600]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Hemorrhage [C23.550.414]
- Purpura [C23.550.414.950]
- Purpura, Thrombocytopenic [C23.550.414.950.687]
- Purpura, Thrombocytopenic, Idiopathic [C23.550.414.950.687.600]
- Signs and Symptoms [C23.888]
- Skin Manifestations [C23.888.885]
- Purpura [C23.888.885.687]
- Purpura, Thrombocytopenic [C23.888.885.687.687]
- Purpura, Thrombocytopenic, Idiopathic [C23.888.885.687.687.600]
Below are MeSH descriptors whose meaning is more specific than "Purpura, Thrombocytopenic, Idiopathic".
This graph shows the total number of publications written about "Purpura, Thrombocytopenic, Idiopathic" by people in this website by year, and whether "Purpura, Thrombocytopenic, Idiopathic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Purpura, Thrombocytopenic, Idiopathic" by people in Profiles.
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Khanuja K, Levy AT, McLaren RA, Berghella V. Pre- and postpregnancy platelet counts: evaluating accuracy of gestational thrombocytopenia and immune thrombocytopenia purpura diagnoses. Am J Obstet Gynecol MFM. 2022 May; 4(3):100606.
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Hurwitz A, Massone R, Lopez BL. Acquired Bleeding Disorders. Hematol Oncol Clin North Am. 2017 12; 31(6):1123-1145.
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Schultz CL, Mitra N, Schapira MM, Lambert MP. Influence of the American Society of Hematology guidelines on the management of newly diagnosed childhood immune thrombocytopenia. JAMA Pediatr. 2014 Oct; 168(10):e142214.
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Callan MB, Werner P, Mason NJ, Meny GM, Raducha MG, Henthorn PS. Polymorphisms in canine platelet glycoproteins identify potential platelet antigens. Comp Med. 2013 Aug; 63(4):348-54.
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Gergis U, Ibrahim M, Al-Kazaz M, Parkash S, Gergis E, Desancho M. Successful treatment with tacrolimus of a patient with severe idiopathic thrombocytopenic purpura after allogeneic bone marrow transplantation. J Clin Oncol. 2012 Sep 10; 30(26):e241-2.
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Psaila B, Bussel JB, Linden MD, Babula B, Li Y, Barnard MR, Tate C, Mathur K, Frelinger AL, Michelson AD. In vivo effects of eltrombopag on platelet function in immune thrombocytopenia: no evidence of platelet activation. Blood. 2012 Apr 26; 119(17):4066-72.
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Psaila B, Bussel JB, Frelinger AL, Babula B, Linden MD, Li Y, Barnard MR, Tate C, Feldman EJ, Michelson AD. Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia. J Thromb Haemost. 2011 Nov; 9(11):2302-10.
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Stolla M, Stefanini L, André P, Ouellette TD, Reilly MP, McKenzie SE, Bergmeier W. CalDAG-GEFI deficiency protects mice in a novel model of Fc? RIIA-mediated thrombosis and thrombocytopenia. Blood. 2011 Jul 28; 118(4):1113-20.
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Reale LD, Besa EC. Rituximab in autoimmune pancytopenia: a case report and review of literature. Ann Hematol. 2007 Dec; 86(12):913-6.
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Nace JE, Nomura JT. Patient with thrombocytopenia. Del Med J. 2006 Aug; 78(8):289-94.