NAD(P)H Dehydrogenase (Quinone)
"NAD(P)H Dehydrogenase (Quinone)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein that reversibly catalyzes the oxidation of NADH or NADPH by various quinones and oxidation-reduction dyes. The enzyme is inhibited by dicoumarol, capsaicin, and caffeine.
| Descriptor ID |
D016660
|
| MeSH Number(s) |
D08.811.682.608.800.500
|
| Concept/Terms |
NAD(P)H Dehydrogenase (Quinone)- NAD(P)H Dehydrogenase (Quinone)
- Quinone Reductase
- Reductase, Quinone
- Phylloquinone Reductase
- Reductase, Phylloquinone
- DT Diaphorase
- Diaphorase, DT
- Menadione Reductase
- Reductase, Menadione
|
Below are MeSH descriptors whose meaning is more general than "NAD(P)H Dehydrogenase (Quinone)".
Below are MeSH descriptors whose meaning is more specific than "NAD(P)H Dehydrogenase (Quinone)".
This graph shows the total number of publications written about "NAD(P)H Dehydrogenase (Quinone)" by people in this website by year, and whether "NAD(P)H Dehydrogenase (Quinone)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
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Below are the most recent publications written about "NAD(P)H Dehydrogenase (Quinone)" by people in Profiles.
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Joseph P, Long DJ, Klein-Szanto AJ, Jaiswal AK. Role of NAD(P)H:quinone oxidoreductase 1 (DT diaphorase) in protection against quinone toxicity. Biochem Pharmacol. 2000 Jul 15; 60(2):207-14.
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Joseph P, Klein-Szanto AJ, Jaiswal AK. Hydroquinones cause specific mutations and lead to cellular transformation and in vivo tumorigenesis. Br J Cancer. 1998 Aug; 78(3):312-20.
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Radjendirane V, Joseph P, Lee YH, Kimura S, Klein-Szanto AJ, Gonzalez FJ, Jaiswal AK. Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity. J Biol Chem. 1998 Mar 27; 273(13):7382-9.