Bone Remodeling

"Bone Remodeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.

Descriptor ID	D016723
MeSH Number(s)	G11.427.213 G16.762.150
Concept/Terms	Bone Remodeling Bone Remodeling Remodeling, Bone Bone Turnover Bone Turnovers Turnover, Bone Turnovers, Bone

Below are MeSH descriptors whose meaning is more general than "Bone Remodeling".

Biological Sciences [G]
Musculoskeletal and Neural Physiological Phenomena [G11]
Musculoskeletal Physiological Phenomena [G11.427]
Bone Remodeling [G11.427.213]
Biological Phenomena [G16]
Regeneration [G16.762]
Bone Remodeling [G16.762.150]

Below are MeSH descriptors whose meaning is more specific than "Bone Remodeling".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bone Remodeling" by people in this website by year, and whether "Bone Remodeling" was a major or minor topic of these publications.

Bar chart showing 24 publications over 13 distinct years, with a maximum of 4 publications in 2008 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	1	1	2
2007	1	0	1
2008	1	3	4
2009	2	1	3
2010	0	1	1
2011	0	1	1
2015	3	1	4
2016	1	1	2
2017	1	0	1
2018	0	1	1
2019	0	1	1
2020	1	1	2
2022	0	1	1

Below are the most recent publications written about "Bone Remodeling" by people in Profiles.

Armstrong A, Mandala A, Malhotra M, Gnana-Prakasam JP. Canonical Wnt Signaling in the Pathology of Iron Overload-Induced Oxidative Stress and Age-Related Diseases. Oxid Med Cell Longev. 2022; 2022:7163326.

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Davidson RK, Himes ER, Takigawa S, Chen A, Horn MR, Meijome T, Wallace JM, Kacena MA, Yokota H, Nguyen AV, Li J. The loss of STAT3 in mature osteoclasts has detrimental effects on bone structure. PLoS One. 2020; 15(7):e0236891.

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Santi L, De Ponti G, Dina G, Pievani A, Corsi A, Riminucci M, Khan S, Sawamoto K, Antolini L, Gregori S, Annoni A, Biondi A, Quattrini A, Tomatsu S, Serafini M. Neonatal combination therapy improves some of the clinical manifestations in the Mucopolysaccharidosis type I murine model. Mol Genet Metab. 2020 07; 130(3):197-208.

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Kamdem LK, Xi J, Clark BL, Gregory BJ, Kidwell KM, Storniolo AM, Stearns V, Hayes DF, Gersch CL, Rae JM, Henry NL, Hertz DL. Exemestane may be less detrimental than letrozole to bone health in women homozygous for the UGT2B17*2 gene deletion. Breast Cancer Res Treat. 2019 Jun; 175(2):297-303.

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Berglund JA, Tella SH, Tuthill KF, Kim L, Guthrie LC, Paul SM, Stanton R, Collins MT, Boyce AM. Scoliosis in Fibrous Dysplasia/McCune-Albright Syndrome: Factors Associated With Curve Progression and Effects of Bisphosphonates. J Bone Miner Res. 2018 09; 33(9):1641-1648.

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Moorer MC, Hebert C, Tomlinson RE, Iyer SR, Chason M, Stains JP. Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation. J Cell Sci. 2017 02 01; 130(3):531-540.

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Gallagher JC, Palacios S, Ryan KA, Yu CR, Pan K, Kendler DL, Mirkin S, Komm BS. Effect of conjugated estrogens/bazedoxifene on postmenopausal bone loss: pooled analysis of two randomized trials. Menopause. 2016 10; 23(10):1083-91.

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Greco PM. Do you believe in magic? Am J Orthod Dentofacial Orthop. 2016 Jun; 149(6):808-9.

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Oesterreich S, Henry NL, Kidwell KM, Van Poznak CH, Skaar TC, Dantzer J, Li L, Hangartner TN, Peacock M, Nguyen AT, Rae JM, Desta Z, Philips S, Storniolo AM, Stearns V, Hayes DF, Flockhart DA. Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover. Breast Cancer Res Treat. 2015 Nov; 154(2):263-73.

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Schultz TC, Valenzano JP, Verzella JL, Umland EM. Odanacatib: an emerging novel treatment alternative for postmenopausal osteoporosis. Womens Health (Lond). 2015 Nov; 11(6):805-14.

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