beta-Thalassemia

"beta-Thalassemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.

Descriptor ID	D017086
MeSH Number(s)	C15.378.071.141.150.875.150 C15.378.420.826.150 C16.320.070.875.150 C16.320.365.826.150
Concept/Terms	beta-Thalassemia beta-Thalassemia Microcytemia, beta Type Microcytemias, beta Type Type Microcytemia, beta Type Microcytemias, beta beta Type Microcytemia beta Type Microcytemias beta Thalassemia Thalassemia, beta Thalassemias, beta beta Thalassemias Thalassemia, beta Type Thalassemias, beta Type Type Thalassemia, beta Type Thalassemias, beta beta Type Thalassemia beta Type Thalassemias Thalassemia Intermedia Thalassemia Intermedia Intermedia, Thalassemia Intermedias, Thalassemia Thalassemia Intermedias Thalassemia Minor Thalassemia Minor Thalassemia Minor (beta-Thalassemia Minor) Minor, Thalassemia (beta-Thalassemia Minor) Minors, Thalassemia (beta-Thalassemia Minor) Thalassemia Minor (beta Thalassemia Minor) Thalassemia Minors (beta-Thalassemia Minor) Hemoglobin F Disease Hemoglobin F Disease Disease, Hemoglobin F Thalassemia Major Thalassemia Major Anemia, Erythroblastic Anemias, Erythroblastic Erythroblastic Anemia Thalassemia Major (beta-Thalassemia Major) Major, Thalassemia (beta-Thalassemia Major) Majors, Thalassemia (beta-Thalassemia Major) Thalassemia Major (beta Thalassemia Major) Thalassemia Majors (beta-Thalassemia Major) Mediterranean Anemia Anemias, Mediterranean Mediterranean Anemias Anemia, Cooley's Anemia, Cooley Anemia, Cooleys Cooley's Anemia Anemia, Mediterranean

Below are MeSH descriptors whose meaning is more general than "beta-Thalassemia".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Anemia [C15.378.071]
Anemia, Hemolytic [C15.378.071.141]
Anemia, Hemolytic, Congenital [C15.378.071.141.150]
Thalassemia [C15.378.071.141.150.875]
beta-Thalassemia [C15.378.071.141.150.875.150]
Hemoglobinopathies [C15.378.420]
Thalassemia [C15.378.420.826]
beta-Thalassemia [C15.378.420.826.150]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Anemia, Hemolytic, Congenital [C16.320.070]
Thalassemia [C16.320.070.875]
beta-Thalassemia [C16.320.070.875.150]
Hemoglobinopathies [C16.320.365]
Thalassemia [C16.320.365.826]
beta-Thalassemia [C16.320.365.826.150]

Below are MeSH descriptors whose meaning is related to "beta-Thalassemia".

Below are MeSH descriptors whose meaning is more specific than "beta-Thalassemia".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "beta-Thalassemia" by people in this website by year, and whether "beta-Thalassemia" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 2 publications in 2002 and 2012 and 2015 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1997	1	0	1
2002	2	0	2
2004	1	0	1
2005	1	0	1
2011	0	1	1
2012	1	1	2
2015	2	0	2
2016	2	0	2
2017	1	0	1
2018	0	1	1
2021	0	1	1
2023	1	0	1

Below are the most recent publications written about "beta-Thalassemia" by people in Profiles.

Parrow NL, Fleming RE. Transferrin receptor 1: keeper of HFE. Blood. 2023 Jan 26; 141(4):332-333.

View in: PubMed
Castro-Mollo M, Gera S, Ruiz-Martinez M, Feola M, Gumerova A, Planoutene M, Clementelli C, Sangkhae V, Casu C, Kim SM, Ostland V, Han H, Nemeth E, Fleming R, Rivella S, Lizneva D, Yuen T, Zaidi M, Ginzburg Y. The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry. Elife. 2021 05 18; 10.

View in: PubMed
Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R, Tran LT, Razon RL, Stark CW, Neumayr LD, Vichinsky EP. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med. 2018 Jul 19; 379(3):226-235.

View in: PubMed
Sood R, Jiramongkolchai K, Streiff M, Gonzalez C, Shanbhag S, Lanzkron S, Arevalo JF, Naik R. Look into my eyes: An unusual first presentation of sickle cell disease. Am J Hematol. 2017 Sep; 92(9):968-971.

View in: PubMed
Casu C, Oikonomidou PR, Chen H, Nandi V, Ginzburg Y, Prasad P, Fleming RE, Shah YM, Valore EV, Nemeth E, Ganz T, MacDonald B, Rivella S. Minihepcidin peptides as disease modifiers in mice affected by ß-thalassemia and polycythemia vera. Blood. 2016 Jul 14; 128(2):265-76.

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Yu TT, Nelson J, Streiff MB, Lanzkron S, Naik RP. Risk factors for venous thromboembolism in adults with hemoglobin SC or S?(+) thalassemia genotypes. Thromb Res. 2016 May; 141:35-8.

View in: PubMed
Chen H, Choesang T, Li H, Sun S, Pham P, Bao W, Feola M, Westerman M, Li G, Follenzi A, Blanc L, Rivella S, Fleming RE, Ginzburg YZ. Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation. Haematologica. 2016 Mar; 101(3):297-308.

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Abdel-Messih IY, Youssef SR, Mokhtar GM, Elmogy MI, Mahmoud HM, Ayoub M, Pessar SA. Clinical to Molecular Screening Paradigm for ?-Thalassemia Carriers. Hemoglobin. 2015; 39(4):240-6.

View in: PubMed
Parrow NL, Gardenghi S, Ramos P, Casu C, Grady RW, Anderson ER, Shah YM, Li H, Ginzburg YZ, Fleming RE, Rivella S. Decreased hepcidin expression in murine ß-thalassemia is associated with suppression of Bmp/Smad signaling. Blood. 2012 Mar 29; 119(13):3187-9.

View in: PubMed
Naik RP, Lanzkron S. Baby on board: what you need to know about pregnancy in the hemoglobinopathies. Hematology Am Soc Hematol Educ Program. 2012; 2012:208-14.

View in: PubMed

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