Receptors, Prostaglandin E
"Receptors, Prostaglandin E" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors which bind prostaglandins with a high affinity and trigger intracellular changes which influence the behavior of cells. Prostaglandin E receptors prefer prostaglandin E2 to other endogenous prostaglandins. They are subdivided into EP1, EP2, and EP3 types based on their effects and their pharmacology.
| Descriptor ID |
D018078
|
| MeSH Number(s) |
D12.776.543.750.695.200.700.600
|
| Concept/Terms |
Receptors, Prostaglandin E- Receptors, Prostaglandin E
- Prostaglandin E Receptors
- E Receptors, Prostaglandin
- PGE2 Receptors
- PGE Receptor
- PGE Receptors
- Prostaglandin E Receptor
- E Receptor, Prostaglandin
- Receptor, Prostaglandin E
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Prostaglandin E".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prostaglandin E".
This graph shows the total number of publications written about "Receptors, Prostaglandin E" by people in this website by year, and whether "Receptors, Prostaglandin E" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Prostaglandin E" by people in Profiles.
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Robertson FM, Simeone AM, Lucci A, McMurray JS, Ghosh S, Cristofanilli M. Differential regulation of the aggressive phenotype of inflammatory breast cancer cells by prostanoid receptors EP3 and EP4. Cancer. 2010 Jun 1; 116(11 Suppl):2806-14.
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Zheng Y, Ritzenthaler JD, Sun X, Roman J, Han S. Prostaglandin E2 stimulates human lung carcinoma cell growth through induction of integrin-linked kinase: the involvement of EP4 and Sp1. Cancer Res. 2009 Feb 01; 69(3):896-904.
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Ritzenthaler JD, Roman J, Han S. PPARbeta/delta agonist increases the expression of PGE2 receptor subtype EP4 in human lung carcinoma cells. Methods Mol Biol. 2009; 512:309-23.
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Robertson FM, Simeone AM, Mazumdar A, Shah AH, McMurray JS, Ghosh S, Cristofanilli M. Molecular and pharmacological blockade of the EP4 receptor selectively inhibits both proliferation and invasion of human inflammatory breast cancer cells. J Exp Ther Oncol. 2008; 7(4):299-312.
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Han S, Ritzenthaler JD, Wingerd B, Rivera HN, Roman J. Extracellular matrix fibronectin increases prostaglandin E2 receptor subtype EP4 in lung carcinoma cells through multiple signaling pathways: the role of AP-2. J Biol Chem. 2007 Mar 16; 282(11):7961-72.
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Li J, Liu D, Ke HZ, Duncan RL, Turner CH. The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J Biol Chem. 2005 Dec 30; 280(52):42952-9.
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Guo M, Pascual RM, Wang S, Fontana MF, Valancius CA, Panettieri RA, Tilley SL, Penn RB. Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms. Biochemistry. 2005 Oct 25; 44(42):13771-82.
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Genetos DC, Geist DJ, Liu D, Donahue HJ, Duncan RL. Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts. J Bone Miner Res. 2005 Jan; 20(1):41-9.
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Han S, Roman J. Suppression of prostaglandin E2 receptor subtype EP2 by PPARgamma ligands inhibits human lung carcinoma cell growth. Biochem Biophys Res Commun. 2004 Feb 20; 314(4):1093-9.
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Tilley SL, Hartney JM, Erikson CJ, Jania C, Nguyen M, Stock J, McNeisch J, Valancius C, Panettieri RA, Penn RB, Koller BH. Receptors and pathways mediating the effects of prostaglandin E2 on airway tone. Am J Physiol Lung Cell Mol Physiol. 2003 Apr; 284(4):L599-606.